Tapimio Depot: Uses, Dosage & Side Effects
A prescription-only 25 mg prolonged-release (depot) tablet taken by mouth. Designed to release its active ingredient gradually over several hours to maintain a steady drug level between doses.
Tapimio Depot is a prescription-only oral medicine supplied as a 25 mg prolonged-release (depot) tablet. The "Depot" part of the name tells you that the tablet is designed to release its active ingredient slowly over several hours, so that drug levels in the body remain more stable and the medicine can usually be taken less often than an immediate-release product. Because prescribing indications, exact dosing schedules, and product-specific warnings for Tapimio Depot must come from the official Summary of Product Characteristics (SmPC) or equivalent local prescribing information, the information below focuses on how to use depot tablets safely, what to watch out for with any prescription medicine, and when to speak to your doctor or pharmacist. Always read the patient information leaflet supplied in the pack and follow the advice of your prescriber.
Quick Facts: Tapimio Depot
Key Takeaways
- Tapimio Depot 25 mg is a prescription-only prolonged-release tablet, meaning it is taken by mouth and releases its active ingredient gradually over several hours rather than all at once.
- Because it is prescription-only, Tapimio Depot must be prescribed by a qualified healthcare professional who decides whether it is appropriate for your specific condition, chooses the dose, and monitors your treatment.
- Depot tablets are generally swallowed whole with water; crushing, breaking, or chewing them can destroy the slow-release mechanism and release the whole dose at once, which may cause harm unless specifically permitted by the prescribing information.
- Always tell your prescriber and pharmacist about every other medicine, supplement, and herbal product you use, as well as any allergies, pregnancy, breastfeeding, or plans to become pregnant, before starting or stopping Tapimio Depot.
- Product-specific information about indications, exact dosing, contraindications, interactions, side-effect frequencies, and storage conditions must come from the official patient information leaflet, Summary of Product Characteristics, or equivalent local label – this page cannot replace those sources.
What Is Tapimio Depot and What Is It Used For?
Tapimio Depot is a brand-name oral medicine that is only available on prescription. Each tablet contains 25 mg of active ingredient and is formulated as a "depot" or "prolonged-release" tablet. In pharmaceutical terminology, the words depot, prolonged-release, sustained-release, extended-release and modified-release are often used interchangeably to describe tablets or capsules that are engineered to release the active drug slowly over an extended period of time, rather than all at once. This helps to keep the amount of drug in the blood within a more stable, therapeutic range between doses.
The benefits of a depot formulation can include fewer doses per day, smoother symptom control, and reduced peak-related side effects that sometimes occur when a large amount of an active ingredient is absorbed quickly from an immediate-release tablet. For people who need to take medicine long term, fewer daily doses can also make it easier to stick to their treatment plan. At the same time, the slow-release design means that missed doses, doubled doses, and inappropriate breaking or crushing of the tablet can all have more significant consequences than with a regular tablet, because they can disrupt the carefully controlled release profile.
Because the regulatory status and the exact conditions that Tapimio Depot is approved to treat can vary between countries and may change over time, this article deliberately does not list specific indications. Your prescriber will have checked the approved, evidence-based use of Tapimio Depot before prescribing it to you. If you are not sure why you have been prescribed Tapimio Depot, it is reasonable and important to ask your doctor or pharmacist. Understanding the reason for your treatment helps you to take the medicine correctly, to recognize side effects, and to know what improvements to expect.
Tapimio Depot is taken orally (by mouth). It is not an injection, an implant, or a long-acting injectable "depot" in the sense sometimes used for certain psychiatric or hormonal medicines; in this case, "Depot" refers to the sustained-release properties of the tablet itself. The 25 mg strength refers to the total amount of active ingredient in each tablet. Depending on the condition being treated and the prescriber's judgement, one or more tablets may be taken per day, or the 25 mg strength may be used as part of a larger multi-strength treatment plan. Always follow the dosing schedule written on your prescription and on the dispensing label rather than assumptions based on the tablet strength alone.
In the context of an oral tablet, "Depot" means the tablet acts as a small drug reservoir inside the digestive tract, releasing its content gradually. This contrasts with a standard tablet that dissolves quickly and delivers the full dose in a short time. The prolonged-release design is achieved through special tablet technologies (for example matrix systems, coated pellets, or osmotic pumps), which are precisely engineered during manufacturing – which is why the tablet should normally be swallowed whole and not altered.
What Should You Know Before Taking Tapimio Depot?
Contraindications
A contraindication is a situation in which a specific medicine should not be used because the risk outweighs any potential benefit. The exact contraindications for Tapimio Depot are listed in its official prescribing information. At a minimum, as with essentially any prescription medicine, Tapimio Depot should not be taken by anyone who has previously had a serious allergic reaction (hypersensitivity) to the active ingredient or to any of the tablet’s excipients. If you have ever had rash, swelling of the face, lips or throat, difficulty breathing, or any other severe reaction after taking this or a related medicine, tell your doctor before receiving a new prescription.
Other situations that can lead to a medicine being contraindicated for an individual patient include certain coexisting diseases, being under a specified age, being pregnant or breastfeeding, or taking particular interacting drugs. Because these details are very product-specific, always go through the "Do not take this medicine if..." section of the official patient information leaflet that comes with your pack, and ask your pharmacist to explain anything that is not clear.
Warnings and Precautions
Prolonged-release (depot) tablets are engineered to release the drug slowly. Breaking, crushing, chewing, grinding, or dissolving a depot tablet can destroy this mechanism and cause the entire 25 mg dose to be absorbed quickly, potentially leading to overdose-type side effects. Do not do any of these things to your Tapimio Depot tablet unless the official patient information leaflet or your prescribing doctor or pharmacist specifically confirms that it is safe for this particular product.
Before and during treatment with Tapimio Depot, make sure your healthcare team is aware of the following:
- Allergies: Any known allergies to medicines, foods, or tablet excipients (such as lactose, gluten, sodium, certain dyes, or polysorbates). If you develop a new rash, itching, swelling, breathing difficulty, or other signs of an allergic reaction during treatment, stop the medicine and seek medical advice without delay.
- Medical history: Any long-term conditions, including liver disease, kidney disease, heart disease, high or low blood pressure, diabetes, thyroid problems, epilepsy, a history of mental health conditions, or any bleeding or clotting disorders. Some of these conditions may require dose adjustment, extra monitoring, or avoidance of the medicine.
- Recent procedures: Any recent or upcoming surgeries, dental procedures, or anaesthetics. Tell the healthcare professional performing the procedure that you are taking Tapimio Depot.
- Older age: Older adults can sometimes be more sensitive to medicines, experience more side effects, and need a lower dose or slower titration. If you are over 65, your prescriber may adjust your treatment.
- Children and adolescents: Many prescription medicines are not studied or approved in younger age groups. Do not give Tapimio Depot to a child, teenager, or anyone else for whom it has not been specifically prescribed.
- Driving and activities requiring concentration: Some medicines can cause drowsiness, dizziness, blurred vision, or slowed reactions. Before driving, cycling, or operating machinery, check how Tapimio Depot affects you and follow the advice in the patient information leaflet.
- Alcohol: Alcohol can change how some medicines work and can increase the risk of side effects, including drowsiness, gastrointestinal irritation, and liver stress. Ask your pharmacist whether alcohol can safely be consumed while taking Tapimio Depot.
- Accurate dosing: Use only the dose prescribed for you. Never share your Tapimio Depot with someone else, even if they appear to have a similar condition, and never take someone else’s prescription medicine.
During treatment, your doctor may ask you to attend regular check-ups or blood tests. Do not skip these appointments, even if you feel well – they help to catch early signs of side effects or inadequate treatment response.
Pregnancy and Breastfeeding
As a general principle, no prescription medicine should be started, continued, or stopped during pregnancy or breastfeeding without explicit medical advice. Some medicines can affect the developing baby or the newborn via breast milk; others are considered acceptable when the benefit to the mother clearly outweighs any potential risk. The specific pregnancy and lactation advice for Tapimio Depot is provided in the official patient information leaflet and Summary of Product Characteristics for this product.
Tell your doctor if you are pregnant, think you might be pregnant, or are planning a pregnancy. Discuss contraception if it might be relevant. If you are breastfeeding, let your doctor know before you start Tapimio Depot so they can consider whether it is appropriate to continue breastfeeding, switch to a different treatment, or time doses carefully. Never stop a prescribed medicine abruptly because you discover you are pregnant – contact your prescriber for tailored advice as soon as possible.
Driving and Operating Machinery
Many oral prescription medicines can cause side effects that affect your ability to drive or to operate machinery safely, such as drowsiness, tiredness, dizziness, blurred vision, or slowed reaction time. Until you know how Tapimio Depot affects you, avoid driving, cycling, operating heavy machinery, or performing other safety-critical tasks. If any of these side effects do occur and persist, tell your doctor; they can review your treatment.
Excipients and Other Ingredients
In addition to the active ingredient, Tapimio Depot 25 mg tablets contain inactive ingredients (excipients) that give the tablet its structure and its slow-release properties. Excipients can include binders, fillers, disintegrants, lubricants, coatings, and colouring agents. A small number of people have allergies or intolerances to specific excipients (for example lactose in lactose intolerance, gluten from wheat starch in coeliac disease, certain azo dyes, or particular sugars). If you are known to react to any specific excipient, check the official patient information leaflet for Tapimio Depot to confirm which ingredients the tablet contains, and speak to your pharmacist if anything is unclear.
How Does Tapimio Depot Interact with Other Drugs?
A drug interaction is any change in the effect or safety of a medicine that is caused by the presence of another substance. Interactions can occur between prescription medicines, with over-the-counter painkillers or cold remedies, with dietary supplements and herbal products (for example St. John’s Wort or grapefruit juice), with certain foods, and with alcohol or recreational drugs. The consequences range from a reduced therapeutic effect to a dangerously increased risk of side effects or toxicity. Because the specific interacting agents for Tapimio Depot should be verified against its up-to-date prescribing information, the table below lists general categories of drug-interaction patterns that are relevant for many prolonged-release oral medicines.
General Interaction Categories to Consider
| Interacting Category | Typical Effect | Practical Advice |
|---|---|---|
| Other prescription medicines | May increase or decrease the amount of active ingredient in the blood, or add to side effects such as sedation, blood pressure changes, or bleeding risk. | Give your doctor and pharmacist a full medication list at every visit, including repeats started elsewhere. |
| Over-the-counter medicines (painkillers, cough/cold remedies, antacids) | Can affect absorption, stomach irritation, kidney function, or sedation levels. | Always ask your pharmacist before buying an over-the-counter product while on Tapimio Depot. |
| Herbal remedies and supplements (e.g. St. John’s Wort, grapefruit juice products, high-dose vitamins) | Can either reduce effectiveness of the medicine or increase blood levels and side effects through effects on liver enzymes. | Tell your healthcare team about any herbal or “natural” products, even if you consider them harmless. |
| Alcohol | May add to drowsiness or dizziness, irritate the stomach, or alter how the liver processes the medicine. | Ask whether alcohol can be taken at all, and if so in what quantity, while on Tapimio Depot. |
| Vaccines | Some medicines can reduce the body’s response to vaccines, or specific vaccines can be contraindicated. | Tell your vaccine provider you take Tapimio Depot before routine or travel vaccination. |
How to Reduce Interaction Risk in Daily Life
Most dangerous drug interactions are preventable with clear communication. Keep an up-to-date written list of everything you take – including dose, strength, and why you take it – and show it at every medical and dental visit. If you have a chronic illness, consider asking one community pharmacy to be your “home” pharmacy, so that one pharmacist has a complete picture of your medicines and can flag potential interactions. Before travelling, ask your prescriber whether any travel health products (anti-malarial tablets, motion-sickness pills, acute-illness antibiotics) are safe with Tapimio Depot.
If you are ever started on a new medicine during a hospital stay, dental visit, or visit to a different specialist, ask that clinician to check the new prescription against your ongoing Tapimio Depot treatment. Do not assume that information automatically flows between systems.
What Is the Correct Dosage of Tapimio Depot?
Because Tapimio Depot is a prescription medicine, the choice of dose is made by a qualified healthcare professional based on the condition being treated, your age and weight, how well your liver and kidneys work, which other medicines you take, and how you respond to treatment. Always follow the exact dose, frequency, and duration shown on your prescription label and in the patient information leaflet. Only a prescriber can change your dose.
How to Take a Depot Tablet Correctly
General Administration Guidance for Prolonged-Release Tablets
Swallow whole: Take the 25 mg tablet with a full glass (at least 150–200 mL) of water. Do not crush, chew, break, or suck the tablet unless the patient information leaflet specifically says you may.
Timing: Try to take Tapimio Depot at roughly the same time(s) each day, which helps keep drug levels stable and makes it easier to remember doses.
Food: Some depot tablets should be taken with food, others on an empty stomach, and others with no specific requirement. Check the patient information leaflet for Tapimio Depot or ask your pharmacist.
Position: Take the tablet sitting or standing upright, and remain upright for at least several minutes afterwards, to reduce the risk of the tablet getting stuck in the oesophagus.
Adults
The dosing schedule for adults depends on the condition being treated and on individual patient factors. The prescriber may start you on a low dose and slowly increase it (titration) or may keep you on a stable dose for a long period. Do not change your dose yourself because you feel better or worse; if your symptoms change significantly, contact your prescriber.
Older Adults
Older adults (especially those over 65–75 years) often require particular care with prescription medicines. Kidney and liver function naturally decline with age, the body may hold on to some drugs longer, and polypharmacy (taking many medicines together) is more common, which increases the risk of interactions. Your doctor may prescribe a lower starting dose of Tapimio Depot, titrate more slowly, or monitor you more closely. Falls, confusion, and unusual drowsiness in an older person starting a new medicine should always be reported.
Children and Adolescents
Many prescription medicines, particularly prolonged-release tablets, are not approved for use in children and adolescents because they have not been studied in this age group, because the dose strength cannot be accurately adjusted for smaller body weights, or because the tablet cannot easily be divided. Do not give Tapimio Depot to a child or teenager unless it has been specifically prescribed for them by a paediatrician or other qualified prescriber who has confirmed it is suitable.
Patients with Liver or Kidney Impairment
The liver and kidneys are the main organs that break down and remove medicines from the body. If either is not working well, drug levels can build up, increasing the risk of side effects. Patients with significant liver disease or kidney disease may need a lower dose of Tapimio Depot, a longer interval between doses, or a different medicine altogether. Always make sure your prescriber knows about any current or past liver or kidney problems, including hepatitis, cirrhosis, chronic kidney disease, or previous abnormal blood tests.
Missed Dose
As a general rule for prolonged-release tablets: if you remember your missed dose on the same day, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your normal schedule. Never take a double dose to make up for a forgotten one. Product-specific guidance may differ – always check the patient information leaflet for Tapimio Depot, and contact your pharmacist or doctor if you are unsure.
If you miss several doses in a row, or have been unable to take Tapimio Depot because of vomiting, illness, or a hospital admission, contact your prescriber before simply resuming your previous schedule. For certain medicines, re-starting suddenly at a full dose after a break can increase side effects and the prescriber may want to re-titrate.
Overdose
If you (or someone else) have taken more Tapimio Depot than prescribed, or if a child accidentally swallows one or more tablets, seek urgent medical advice immediately. Call your local emergency number, your national poisons information centre, or go to the nearest emergency department, and bring the medicine pack with you. Do not wait for symptoms to appear. Symptoms of an overdose of a prolonged-release tablet can sometimes be delayed, because the drug continues to be absorbed over several hours.
Keep emergency numbers and poison-centre information in your phone and on your fridge, especially if there are young children or vulnerable adults in the home. Store Tapimio Depot out of their sight and reach at all times.
Stopping Treatment
Do not stop taking Tapimio Depot suddenly unless your doctor tells you to. Some medicines cause withdrawal or rebound symptoms if stopped abruptly, and in other cases the underlying condition can return or worsen. If you want to stop for any reason – including side effects, cost, pregnancy, or travel – speak to your prescriber first. Together you can plan how to stop safely, and if another treatment is needed.
What Are the Side Effects of Tapimio Depot?
Side effects (also called adverse drug reactions) are any unwanted effects that can occur when you take a medicine. They range from mild and temporary (such as a slight headache or nausea for a few days) to severe or life-threatening (such as a severe allergic reaction or organ damage). Regulatory authorities such as the European Medicines Agency (EMA) group side effects by how commonly they occur, using the following frequency categories.
Very Common
May affect more than 1 in 10 people
- Effects seen in a large proportion of patients during clinical trials.
- Usually listed first in the patient information leaflet.
- For Tapimio Depot, specific very common effects must be confirmed in the official leaflet.
Common
May affect up to 1 in 10 people
- Occur frequently enough to be documented in clinical trials, but not in the majority of patients.
- Examples across oral prescription medicines typically include effects such as headache, nausea, or tiredness.
- See the Tapimio Depot patient information leaflet for the specific common effects reported for this product.
Uncommon
May affect up to 1 in 100 people
- Occur less frequently but are still formally recognized in the product label.
- Report any new unusual symptom to your doctor, even if it seems mild at first.
Rare
May affect up to 1 in 1,000 people
- Uncommon but acknowledged in the prescribing information.
- Can include more serious effects; always read the "When to seek urgent medical attention" section of the leaflet.
Very Rare / Not Known
Affects fewer than 1 in 10,000 people, or frequency cannot be estimated
- Includes effects reported only in post-marketing surveillance.
- Some may be serious but exceedingly uncommon – do not assume you will be affected.
Serious Symptoms That Always Require Urgent Medical Attention
Regardless of what the patient information leaflet says, any of the following symptoms after taking a new prescription medicine require immediate medical review, often by calling your local emergency number or attending an emergency department:
- Signs of a severe allergic reaction (anaphylaxis): swelling of the face, lips, tongue or throat, difficulty breathing or swallowing, rapid pulse, faintness, widespread rash or hives.
- Sudden chest pain, shortness of breath, palpitations, or signs of stroke such as sudden weakness of the face or one side of the body, slurred speech, or severe headache.
- Yellowing of the skin or eyes (jaundice), very dark urine, pale stools, or severe upper-right abdominal pain – possible signs of liver problems.
- Severe or persistent vomiting, blood in vomit or stools, or black tarry stools.
- Severe skin reactions with blistering, peeling, or involvement of the mouth, eyes, or genitals (possible Stevens-Johnson syndrome or similar severe skin reactions).
- New thoughts of self-harm, severe low mood, agitation, confusion, or hallucinations.
- Fever of unknown cause, especially with sore throat or mouth ulcers, which might indicate a blood cell problem.
Reporting Side Effects
If you experience any side effect, including one not listed in the patient information leaflet, tell your doctor, pharmacist, or nurse. You can also report suspected side effects directly to your national medicines regulator – for example, through the EMA’s EudraVigilance system in the European Union, the FDA MedWatch programme in the United States, the MHRA Yellow Card scheme in the United Kingdom, or the equivalent national body in your country. Reporting side effects helps regulators continue to monitor the benefit-risk profile of all medicines.
How Should Tapimio Depot Be Stored?
Correct storage keeps a medicine both safe and effective until its expiry date. Oral prolonged-release tablets are generally sensitive to heat and humidity, because temperature swings and moisture can damage the coating or matrix that controls slow release. For this reason, bathrooms and kitchens are often not the best places to store medicines, despite being convenient.
- Temperature: Store at the temperature written on the pack. Most oral tablets are stored below 25 °C or below 30 °C at room temperature, but always check the Tapimio Depot pack and leaflet for the exact condition.
- Original packaging: Keep the tablets in their original blister or bottle until you are ready to take a dose. This protects them from light and moisture and preserves the expiry date information.
- Humidity and light: Avoid bathrooms, windowsills, and car interiors, where humidity and temperature changes can be extreme.
- Out of reach of children: Store the pack in a locked or high cupboard if there are small children at home. A single adult-strength tablet can be very harmful to a small child.
- Travel: When travelling, keep Tapimio Depot in your carry-on luggage with a copy of your prescription; avoid leaving it in a hot car or checked baggage that might reach extreme temperatures.
- Expiry date: Do not take Tapimio Depot after the expiry date printed on the pack. The expiry date refers to the last day of that month unless otherwise stated.
- Disposal: Do not throw unused or expired tablets in household rubbish or pour them down the sink or toilet. Return them to a pharmacy for environmentally safe disposal, in line with your local take-back scheme.
If you are unsure whether a pack of tablets has been stored correctly (for example after a heatwave, a flooded cupboard, or a long courier delay), ask your pharmacist whether it is still safe to use.
What Does Tapimio Depot Contain?
Active Substance
The active ingredient is the component of the tablet that produces the therapeutic effect. Each Tapimio Depot prolonged-release tablet contains 25 mg of its active substance. “Prolonged-release” means that the release of this active ingredient is gradual after the tablet is swallowed, rather than all at once.
Inactive Ingredients (Excipients)
Excipients are the ingredients in a tablet other than the active substance. They may include:
- Fillers and diluents that give the tablet its size and shape.
- Binders that hold the tablet together.
- Release-modifying polymers that control how quickly the active ingredient is released.
- Disintegrants, lubricants, and glidants that help the tablet be manufactured and swallowed.
- Film coatings, which may contain small amounts of colourings or protective polymers.
The precise list of excipients for Tapimio Depot 25 mg is given in the patient information leaflet supplied in the pack. If you have a known allergy or intolerance to a specific excipient (for example lactose, gluten from wheat starch, certain azo dyes, or polysorbate), check that list before you take the medicine, or ask your pharmacist to check it with you.
Appearance and Pack Sizes
Tapimio Depot is supplied as prolonged-release tablets for oral use. The exact appearance (shape, colour, and any markings) and the available pack sizes are described in the patient information leaflet. If the tablets you receive from the pharmacy look different from what you expect – or noticeably different from tablets from a previous pack – ask the pharmacist to confirm that the product is correct before you start taking them.
Marketing Authorisation and Manufacturer
The marketing authorisation holder and manufacturer are listed at the end of the patient information leaflet. The availability of Tapimio Depot, together with its licensed indications and any restrictions, depends on the regulatory authority in each country. If you have questions about authenticity or supply, your pharmacist or the marketing authorisation holder’s customer service department can help.
Frequently Asked Questions About Tapimio Depot
In this product, “Depot” refers to the tablet being a prolonged-release (also called sustained-release or extended-release) formulation. After you swallow it, the tablet releases its 25 mg of active ingredient gradually over several hours rather than all at once, which helps to keep the amount of drug in your body more constant. It does not mean that the medicine is an injection; Tapimio Depot is taken by mouth.
As a general rule for prolonged-release tablets, you should swallow them whole with water and not crush, chew, break, or grind them. Altering the tablet can destroy the slow-release mechanism and cause the entire dose to be absorbed quickly, which may cause harm. Only split or crush Tapimio Depot if the patient information leaflet or your prescribing doctor or pharmacist specifically confirms this is safe for this product. If you have difficulty swallowing tablets, speak to your doctor or pharmacist about possible alternatives instead of altering the tablet yourself.
General guidance for prolonged-release tablets is to take a missed dose as soon as you remember on the same day, unless it is nearly time for the next dose – in which case you should skip the missed dose and continue with your normal schedule. Never take a double dose to make up for a forgotten one. The specific missed-dose instructions for Tapimio Depot are provided in its patient information leaflet. Setting a daily alarm or using a weekly pill box can help prevent missed doses in the first place.
It depends on the product, your other medicines, and your personal health. Alcohol can interact with many prescription medicines, sometimes increasing drowsiness, stomach irritation, or stress on the liver. Some medicines should be avoided completely with alcohol; others allow moderate amounts. Before drinking any alcohol while on Tapimio Depot, ask your prescriber or pharmacist for product-specific advice, and be especially careful when starting a new medicine, when adjusting the dose, or when combining it with other drugs that cause drowsiness.
No prescription medicine should be started, continued, or stopped during pregnancy or breastfeeding without explicit medical advice. Some medicines can affect the developing baby or the nursing infant; others are considered acceptable when the benefit to the mother outweighs the risk. If you are pregnant, think you may be pregnant, are planning a pregnancy, or are breastfeeding, tell your doctor before you start Tapimio Depot, so they can check the pregnancy and lactation guidance in the official product information and decide the safest course of action with you.
Seek urgent medical help straight away – call your local emergency number, contact a poisons information centre, or go to the nearest emergency department. Bring the Tapimio Depot pack with you so the team can see the exact product, strength, and number of tablets taken. Do not wait for symptoms to appear, because the prolonged-release design means drug absorption can continue for hours. If a child has swallowed tablets intended for an adult, treat this as an emergency even if the child looks well.
No. Do not stop taking Tapimio Depot, or any prescription medicine, without talking to your doctor. Some conditions are treated long term and can return if the medicine is stopped abruptly. Some medicines also cause withdrawal or rebound effects if stopped suddenly. If you feel better, that may be a sign the medicine is working – which is often a reason to continue, not to stop. If you feel worse, are struggling with side effects, or have practical difficulties (for example with cost or supply), contact your prescriber so a proper plan can be made.
References
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- U.S. Food and Drug Administration (FDA). Guidance for Industry: SUPAC-MR: Modified Release Solid Oral Dosage Forms. Rockville, MD: FDA Center for Drug Evaluation and Research; 1997.
- U.S. Food and Drug Administration (FDA). Drugs@FDA: Approved drug products and labelling. Available from: Drugs@FDA.
- Joint Formulary Committee. British National Formulary (BNF). London: BMJ Group and Royal Pharmaceutical Society; 2025. Available from: bnf.nice.org.uk.
- World Health Organization (WHO). WHO Model List of Essential Medicines – 23rd List. Geneva: WHO; 2023.
- World Health Organization (WHO). The Safety of Medicines in Public Health Programmes: Pharmacovigilance, an essential tool. Geneva: WHO; 2006.
- National Institute for Health and Care Excellence (NICE). Medicines optimisation: the safe and effective use of medicines. NICE guideline NG5. London: NICE; 2015.
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Editorial Team
This article was written and reviewed by the iMedic Medical Editorial Team, comprising licensed specialist physicians and clinical pharmacists with expertise in medicines information and drug safety.
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