Pregabalin: Uses, Dosage & Side Effects
A prescription anticonvulsant used for neuropathic pain, epilepsy, and generalized anxiety disorder in adults
Pregabalin is a prescription anticonvulsant medication used to treat peripheral and central neuropathic pain, epilepsy (as adjunctive therapy for partial seizures), and generalized anxiety disorder in adults. A structural analogue of GABA, pregabalin works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters. It is considered more potent and pharmacokinetically predictable than the related drug gabapentin. While effective for its approved indications, pregabalin carries risks of dependency, sedation, dizziness, and withdrawal symptoms if stopped abruptly. It requires careful dose adjustment in patients with kidney problems.
Quick Facts: Pregabalin
Key Takeaways
- Pregabalin is approved for three indications in adults: peripheral and central neuropathic pain, adjunctive therapy for partial seizures (epilepsy), and generalized anxiety disorder (GAD).
- Never stop taking pregabalin suddenly; abrupt discontinuation can trigger withdrawal symptoms including insomnia, headache, nausea, anxiety, diarrhea, flu-like symptoms, and seizures. Always taper gradually over at least one week.
- Pregabalin carries a recognized risk of dependency and is classified as a controlled substance in many countries (Schedule V in the US, Class C in the UK).
- Combining pregabalin with opioids or other CNS depressants significantly increases the risk of respiratory depression, sedation, coma, and death.
- Pregabalin should not be used during pregnancy unless clearly necessary, as studies have shown an increased risk of birth defects when used during the first trimester.
What Is Pregabalin and What Is It Used For?
Pregabalin is a prescription medication that belongs to the anticonvulsant (anti-epileptic) drug class. First approved by the European Medicines Agency (EMA) in 2004 and by the U.S. Food and Drug Administration (FDA) in December 2004 under the brand name Lyrica, it has since become one of the most widely prescribed medications for neuropathic pain and is available globally as a generic drug from numerous manufacturers including Pregabalin Zentiva, Pregabalin Accord, Pregabalin Orion Pharma, Pregabalin Jubilant, Pregabalin CNX Therapeutics, Pregabalin Viatris Pharma, and Pregabalin Krka.
Structurally, pregabalin is a lipophilic analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Despite this structural relationship, pregabalin does not bind to GABA receptors, is not converted into GABA within the body, and does not directly affect GABA uptake or degradation. Its primary mechanism of action involves potent binding to the alpha-2-delta (α2δ) subunit of voltage-gated calcium channels throughout the central nervous system. By reducing calcium influx at presynaptic nerve terminals, pregabalin decreases the release of several excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This mechanism underlies its anticonvulsant, analgesic, and anxiolytic properties. Pregabalin is pharmacologically related to gabapentin but has approximately 2–4 times greater binding affinity for the alpha-2-delta subunit and demonstrates more predictable, linear pharmacokinetics.
Pregabalin is officially approved for three primary indications. The first is peripheral and central neuropathic pain in adults. Peripheral neuropathic pain results from damage to nerves outside the brain and spinal cord, caused by conditions such as diabetes (diabetic polyneuropathy) or shingles (postherpetic neuralgia). Central neuropathic pain arises from damage within the central nervous system itself, for example following spinal cord injury. Patients often describe this pain as burning, shooting, stabbing, sharp, cramping, aching, tingling, or numbness. Neuropathic pain is frequently accompanied by mood disturbances, sleep problems, fatigue, and reduced quality of life, all of which pregabalin can help improve.
The second approved indication is epilepsy. Pregabalin is used as adjunctive (add-on) therapy for partial (focal) seizures with or without secondary generalization in adults. It is important to note that pregabalin is not intended for use as monotherapy (sole treatment) for epilepsy; it must always be taken in combination with other anti-epileptic drugs. Your physician will prescribe pregabalin when your current epilepsy medication does not adequately control your seizures.
The third approved indication is generalized anxiety disorder (GAD) in adults. GAD is characterized by excessive, persistent worry and anxiety that is difficult to control and lasts for at least six months. Symptoms include restlessness, feeling keyed up or on edge, easy fatigability, difficulty concentrating, irritability, muscle tension, and sleep disturbance. Pregabalin has demonstrated efficacy in reducing both the psychological and physical symptoms of GAD in multiple randomized controlled trials. Unlike many other anxiety treatments such as selective serotonin reuptake inhibitors (SSRIs), pregabalin can provide noticeable anxiolytic effects within the first week of treatment due to its rapid absorption and onset of action.
Beyond its approved indications, pregabalin is sometimes prescribed off-label for conditions including fibromyalgia (approved by the FDA in the United States but not by the EMA in Europe), restless legs syndrome, chronic pain syndromes, social anxiety disorder, and alcohol withdrawal. While evidence supports some of these uses, off-label prescribing should always be carefully considered by the treating physician, weighing the potential benefits against risks including dependency and adverse effects.
Pregabalin is available as hard capsules in eight strengths: 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, and 300 mg. All capsules are taken orally with water and can be administered with or without food. The wide range of available strengths allows for flexible dose titration tailored to each patient's individual needs and tolerability.
What Should You Know Before Taking Pregabalin?
Contraindications
Pregabalin must not be used if you have a known allergy (hypersensitivity) to pregabalin or any of the inactive ingredients in the formulation. Inactive ingredients include lactose monohydrate, maize starch, talc, gelatin, titanium dioxide (E171), sodium lauryl sulfate, colloidal anhydrous silica, and various colouring agents depending on capsule strength. If you are intolerant to certain sugars (such as lactose), consult your doctor before taking this medication. Pregabalin contains less than 1 mmol (23 mg) of sodium per capsule, making it essentially sodium-free.
Warnings and Precautions
Pregabalin carries a recognized risk of dependency. Some patients may develop a compulsive need to continue taking the medication beyond the prescribed duration and dose. Withdrawal symptoms including insomnia, headache, nausea, anxiety, diarrhea, flu-like symptoms, nervousness, depression, pain, sweating, dizziness, and seizures can occur if pregabalin is stopped abruptly. Always taper the dose gradually over at least one week under medical supervision.
Before starting pregabalin, it is essential to inform your healthcare provider about your complete medical history. Several conditions require special attention, potentially adjusted dosing, or more frequent monitoring:
- Kidney problems: Pregabalin is eliminated almost entirely through the kidneys. If you have reduced kidney function, your doctor will prescribe a lower dose and a modified dosing schedule to prevent drug accumulation and toxicity. If you notice decreased urination during treatment, inform your doctor as this may resolve upon discontinuation.
- Heart disease: Heart failure has been reported in some patients taking pregabalin, particularly elderly patients with cardiovascular disease. Inform your doctor if you have any history of heart problems before starting treatment.
- History of substance abuse: Individuals with a history of alcohol, prescription drug, or illicit substance abuse are at significantly higher risk of developing pregabalin dependency. Your prescriber should be aware of this history and may consider alternative treatments or closer monitoring.
- Respiratory conditions: Pregabalin can cause breathing difficulties, especially when combined with other central nervous system (CNS) depressants such as opioids, benzodiazepines, or alcohol. Patients with neurological disorders, respiratory diseases, impaired kidney function, or those aged over 65 may be at particular risk and may require a different dosing regimen.
- Age over 65: Elderly patients may be more susceptible to pregabalin's sedative effects and the associated risk of falls, fractures, and dizziness. Your doctor may prescribe a different dosage if you are over 65, particularly if you have any degree of kidney impairment.
- Diabetes: Some patients who gain weight while taking pregabalin may need adjustments to their diabetes medications. Monitor your blood sugar levels closely and consult your doctor if your diabetes control changes.
- Liver disease: Although pregabalin undergoes minimal hepatic metabolism, encephalopathy (impaired brain function) has been reported in some patients with underlying liver or kidney disease. Inform your doctor about any liver conditions.
- Spinal cord injury: Patients with spinal cord injuries who take pregabalin alongside other medications for pain or spasticity may experience enhanced side effects such as excessive drowsiness, as these medications share similar adverse effect profiles.
A small number of people treated with anti-epileptic drugs, including pregabalin, have experienced thoughts of self-harm or suicidal behavior. If you or someone you know develops unusual changes in mood, behavior, or thoughts of self-harm while taking pregabalin, contact a healthcare provider immediately.
Signs of dependency: You should be aware of the following signs that may indicate you are becoming dependent on pregabalin and discuss them with your doctor if they occur:
- Feeling a need to take the medication for longer than prescribed
- Feeling that you need more than the recommended dose
- Using the medication for reasons other than those for which it was prescribed
- Making repeated, unsuccessful attempts to stop or control your use
- Feeling unwell when you stop taking the medication and feeling better when you resume
Allergic reactions: Some patients treated with pregabalin have reported symptoms suggestive of allergic reactions, including swelling of the face, lips, tongue, and throat, as well as diffuse skin rash. Serious skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis, have been reported. If you experience any swelling, rash, blistering, or peeling skin, stop taking pregabalin and seek immediate medical attention.
Vision changes: Pregabalin can cause blurred vision, reduced visual acuity, or other visual disturbances. Most of these changes are temporary. Contact your doctor immediately if you experience any change in your vision during treatment.
Pregnancy and Breastfeeding
Pregabalin should not be used during pregnancy unless clearly necessary and advised by your doctor. Studies examining data from women in Nordic countries who took pregabalin during the first three months of pregnancy found that approximately 6 out of 100 babies had birth defects requiring medical treatment, compared to 4 out of 100 babies in the general population. Reported malformations include cleft lip and palate, eye defects, nervous system abnormalities (including brain malformations), kidney defects, and genital abnormalities.
Women of childbearing potential must use effective contraception during treatment with pregabalin. If you are pregnant, think you may be pregnant, are breastfeeding, or are planning to become pregnant, consult your doctor before using this medication. Pregabalin should not be used during breastfeeding unless your doctor has advised otherwise. If you have epilepsy, never stop your anti-epileptic medication abruptly without medical guidance, as uncontrolled seizures pose serious risks to both mother and baby.
Children and Adolescents
The safety and efficacy of pregabalin in children and adolescents under 18 years of age have not been established. Pregabalin should therefore not be used in this age group.
How Does Pregabalin Interact with Other Drugs?
Inform your doctor or pharmacist about all medications you are currently taking, have recently taken, or plan to take. While pregabalin has relatively few pharmacokinetic drug interactions (it does not significantly affect liver enzymes and is not highly protein-bound), its pharmacodynamic interactions with other central nervous system depressants are clinically significant and potentially life-threatening.
Major Interactions
| Interacting Drug/Class | Effect | Clinical Significance |
|---|---|---|
| Opioid analgesics (e.g., oxycodone, morphine, fentanyl, codeine) | Enhanced CNS depression, respiratory depression, profound sedation | Potentially fatal. Use lowest effective doses; monitor breathing closely |
| Benzodiazepines (e.g., lorazepam, diazepam, alprazolam) | Increased sedation, dizziness, respiratory depression | High risk. Avoid combination if possible; reduce doses |
| Alcohol | Enhanced sedation, dizziness, impaired cognitive and motor function | Patients should be advised not to drink alcohol during treatment |
| Other CNS depressants (sedative antihistamines, barbiturates, muscle relaxants) | Additive sedation, increased risk of falls and respiratory depression | Use caution; monitor for excessive sedation |
The combination of pregabalin with opioid medications is of particular clinical concern. When taken together with opioids including oxycodone, the degree of dizziness, drowsiness, and impaired concentration becomes substantially more pronounced. Cases of impaired breathing, coma, and death have been reported when pregabalin is used concurrently with opioid analgesics. If your doctor determines that both medications are necessary, the lowest effective doses should be prescribed and you should be closely monitored for signs of respiratory depression and excessive sedation.
Minor Interactions
Pregabalin can be taken simultaneously with oral contraceptives (birth control pills) without affecting their efficacy. It does not significantly interact with most common medications used for diabetes, hypertension, or infections. However, because pregabalin may enhance the sedating effects of any medication that acts on the central nervous system, always inform your doctor about your complete medication list.
Medications that may cause constipation (such as certain opioid pain medications) may lead to gastrointestinal problems including severe constipation, blocked bowels, or ileus when taken together with pregabalin. Inform your doctor if you develop constipation, especially if you are predisposed to this problem.
Driving and Operating Machinery
Pregabalin can cause dizziness, drowsiness, and impaired concentration. You should not drive, operate complex machinery, or engage in other potentially hazardous activities until you know how this medication affects your ability to perform these tasks. The combination of pregabalin with alcohol or other sedating medications further increases this impairment.
What Is the Correct Dosage of Pregabalin?
Always take pregabalin exactly as your doctor has instructed. Do not take more than prescribed. Pregabalin capsules should be swallowed whole with water and can be taken with or without food. Consult your doctor or pharmacist if you are unsure about your dose.
Adults
| Indication | Starting Dose | Usual Dose Range | Maximum Dose |
|---|---|---|---|
| Neuropathic Pain | 150 mg/day (divided into 2–3 doses) | 150–600 mg/day | 600 mg/day |
| Epilepsy (adjunctive) | 150 mg/day (divided into 2–3 doses) | 150–600 mg/day | 600 mg/day |
| Generalized Anxiety Disorder | 150 mg/day (divided into 2–3 doses) | 150–600 mg/day | 600 mg/day |
For all indications, the starting dose is typically 150 mg per day, divided into either two doses (morning and evening) or three doses (morning, afternoon, and evening). Your doctor may increase the dose after three to seven days based on your response and tolerability. The dose can be increased to 300 mg per day after one week, and if necessary, to the maximum dose of 600 mg per day after an additional week. When dosing twice daily, take the doses at approximately the same time each morning and evening. When dosing three times daily, take at approximately the same times each morning, afternoon, and evening.
It is important to continue taking pregabalin until your doctor tells you to stop. If you feel the effect of pregabalin is too strong or too weak, consult your doctor or pharmacist for advice.
Elderly Patients
If you are over 65 years of age, you should take pregabalin at the normal adult dose unless you have impaired kidney function, in which case your doctor will prescribe a reduced dose. Elderly patients should be monitored more closely for dizziness, drowsiness, and fall risk.
Patients with Kidney Impairment
Since pregabalin is eliminated almost entirely through the kidneys, patients with reduced kidney function (renal impairment) require dose adjustments. Your doctor will calculate the appropriate dose based on your creatinine clearance, a measure of kidney function. If you are receiving hemodialysis, your doctor will prescribe a supplementary dose after each dialysis session.
Missed Dose
It is important to take your pregabalin capsules regularly at the same times each day. If you forget to take a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a forgotten dose.
Overdose
If you take more pregabalin than prescribed, contact your doctor immediately or go to the nearest emergency department. Bring your pregabalin capsules with you. Overdose symptoms may include drowsiness, confusion, agitation, restlessness, seizures, and loss of consciousness (coma).
What Are the Side Effects of Pregabalin?
Like all medicines, pregabalin can cause side effects, although not everybody gets them. The following is a comprehensive overview of reported side effects organized by frequency. If you experience any of these side effects, especially those that are severe or persistent, consult your healthcare provider.
Very Common
May affect more than 1 in 10 people
- Dizziness
- Drowsiness (somnolence)
- Headache
Common
May affect up to 1 in 10 people
- Increased appetite and weight gain
- Euphoria, confusion, disorientation, decreased libido, irritability
- Impaired attention, clumsiness, memory disturbance, tremor, difficulty speaking, tingling, numbness, sedation, insomnia, fatigue, feeling abnormal
- Blurred vision, double vision
- Vertigo, balance problems, falls
- Dry mouth, constipation, vomiting, flatulence, diarrhea, nausea, abdominal distension
- Erectile dysfunction
- Peripheral edema (swelling of hands, feet, and ankles)
- Feeling of intoxication, gait disturbance
- Muscle cramp, joint pain, back pain, limb pain
- Nasopharyngitis (sore throat)
Uncommon
May affect up to 1 in 100 people
- Decreased appetite, weight loss, low or high blood sugar
- Depersonalization, restlessness, depression, agitation, mood swings, hallucinations, panic attacks, apathy, aggression, elevated mood, difficulty thinking, increased libido, sexual dysfunction including inability to reach orgasm, delayed ejaculation
- Visual changes, unusual eye movements, tunnel vision, light flashes, jerky movements, reduced reflexes, hyperactivity, dizziness on standing, sensitive skin, loss of taste, burning sensation, tremor on movement, reduced consciousness, fainting, increased sensitivity to noise
- Dry eyes, eye swelling, eye pain, watery eyes
- Heart rhythm disturbances, increased heart rate, low or high blood pressure, heart failure
- Flushing, hot flushes
- Breathing difficulty, nosebleed, nasal congestion, snoring, cough
- Increased saliva, heartburn, numbness around the mouth
- Sweating, rash, chills, fever
- Muscle twitching, joint swelling, muscle stiffness, neck pain
- Breast tenderness, urinary difficulty or incontinence
- Weakness, thirst, chest tightness
- Changes in blood test results (liver enzymes, creatine phosphokinase, platelets, blood creatinine, potassium)
- Hypersensitivity, facial swelling, itching, hives
- Painful menstruation, cold hands and feet
Rare
May affect up to 1 in 1,000 people
- Abnormal sense of smell, visual disturbances including depth perception changes, visual brightness changes, visual loss
- Dilated pupils, cross-eyes
- Cold sweat, throat tightness, tongue swelling
- Inflammation of the pancreas (pancreatitis)
- Difficulty swallowing
- Slow or decreased body movement (Parkinsonism symptoms)
- Fluid in the abdomen (ascites) or lungs
- Seizures
- ECG changes corresponding to heart rhythm disturbances
- Muscle damage (rhabdomyolysis)
- Breast discharge, abnormal breast growth
- Kidney failure, decreased urine output
- Decreased white blood cell count
- Inappropriate behavior, suicidal behavior, suicidal thoughts
- Allergic reactions including breathing difficulty, keratitis (eye inflammation)
- Stevens-Johnson syndrome, toxic epidermal necrolysis
- Jaundice (yellowing of skin and eyes)
Very Rare
May affect up to 1 in 10,000 people
- Liver failure
- Hepatitis (liver inflammation)
After stopping short-term or long-term treatment with pregabalin, you may experience withdrawal symptoms including sleep problems, headache, nausea, anxiety, diarrhea, flu-like symptoms, seizures, nervousness, depression, thoughts of self-harm, pain, sweating, and dizziness. These symptoms may be more frequent and pronounced if you have been taking pregabalin for a longer period. If you experience withdrawal symptoms, contact your doctor.
Breathing difficulties: Respiratory depression (shallow breathing) has been reported as a post-marketing side effect. If you have a nervous system disorder, respiratory disease, impaired kidney function, or are over 65, your doctor may prescribe a different dosing regimen. Contact your doctor if you experience breathing difficulties or unusually shallow breathing.
Reporting side effects: If you experience any side effects, including those not listed above, talk to your doctor or pharmacist. You can also report suspected side effects to your national medicines regulatory authority to help monitor the ongoing safety of this medication.
How Should You Store Pregabalin?
Keep pregabalin capsules out of the sight and reach of children at all times. Do not use this medicine after the expiry date which is printed on the carton or bottle after “EXP.” The expiry date refers to the last day of that month.
Pregabalin does not require any special storage conditions. It can be stored at room temperature. Protect the capsules from excessive moisture and heat.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help protect the environment.
What Does Pregabalin Contain?
The active substance in each capsule is pregabalin. Hard capsules are available in eight strengths: 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, and 300 mg.
The other ingredients (excipients) are: lactose monohydrate, maize starch, talc, gelatin, titanium dioxide (E171), sodium lauryl sulfate, colloidal anhydrous silica, black ink (containing shellac, black iron oxide E172, propylene glycol, potassium hydroxide), and water. Capsules of certain strengths (75 mg, 100 mg, 200 mg, 225 mg, and 300 mg) also contain red iron oxide (E172) as a colouring agent.
Pregabalin capsules are available in various pack sizes including blister packs of 14, 21, 56, 70, 84, 100, and 112 capsules, as well as unit-dose blister packs of 100 capsules. Some strengths are also available in HDPE bottles containing 200 capsules. Not all pack sizes may be marketed in your country.
Frequently Asked Questions About Pregabalin
Pregabalin is approved for three main conditions in adults: peripheral and central neuropathic pain (long-term nerve pain from diabetes, shingles, spinal cord injury, or other causes), epilepsy (as adjunctive therapy for partial seizures with or without secondary generalization), and generalized anxiety disorder (GAD). In the United States, pregabalin is also FDA-approved for fibromyalgia. It is sometimes prescribed off-label for other conditions including restless legs syndrome, social anxiety, and chronic pain syndromes.
Yes, dependency on pregabalin is possible, particularly in individuals with a history of substance abuse. Pregabalin is classified as a Schedule V controlled substance in the United States and a Class C controlled drug in the United Kingdom due to dependency and misuse concerns. Withdrawal symptoms such as insomnia, headache, nausea, anxiety, diarrhea, flu-like symptoms, and seizures can occur if the medication is stopped abruptly. Always taper gradually over at least one week under medical supervision.
The most common side effects (affecting more than 1 in 10 people) are dizziness, drowsiness, and headache. Common side effects (affecting up to 1 in 10 people) include increased appetite, weight gain, blurred vision, double vision, dry mouth, constipation, nausea, vomiting, peripheral edema (swelling of hands and feet), fatigue, feeling of intoxication, and impaired coordination. Most side effects are mild to moderate and tend to improve as your body adjusts to the medication.
Combining pregabalin with opioids (such as oxycodone, morphine, fentanyl, or codeine) significantly increases the risk of severe drowsiness, sedation, respiratory depression, coma, and death. If both medications are medically necessary, your doctor should prescribe the lowest effective doses and closely monitor you for signs of respiratory depression and excessive sedation. Always inform your healthcare provider about all medications you are taking.
The onset of action depends on the condition being treated. For neuropathic pain, some patients notice improvement within the first week, but it can take two to four weeks at an effective dose for meaningful pain relief. For generalized anxiety disorder, pregabalin may provide some relief within the first week due to its rapid absorption. For epilepsy, seizure reduction typically becomes apparent within two to four weeks as the dose is gradually increased. The dose is usually titrated upward over one to two weeks to minimize side effects.
Pregabalin should not be used during pregnancy unless clearly necessary. Studies from Nordic countries found that approximately 6 out of 100 babies exposed to pregabalin during the first trimester had birth defects requiring medical treatment, compared to 4 out of 100 in the general population. Reported defects include cleft lip/palate, eye defects, nervous system and brain malformations, kidney defects, and genital abnormalities. Women of childbearing potential must use effective contraception during treatment. If you have epilepsy, never stop your medication abruptly during pregnancy without medical guidance.
References
- 1 European Medicines Agency (EMA). Lyrica (Pregabalin) – Summary of Product Characteristics. Last updated 2024. Available at: ema.europa.eu
- 2 U.S. Food and Drug Administration (FDA). Lyrica (Pregabalin) Capsules – Prescribing Information. Revised 2023. Available at: accessdata.fda.gov
- 3 National Institute for Health and Care Excellence (NICE). Neuropathic Pain in Adults: Pharmacological Management in Non-specialist Settings (CG173). Updated 2024. Available at: nice.org.uk
- 4 National Institute for Health and Care Excellence (NICE). Generalised Anxiety Disorder and Panic Disorder in Adults: Management (CG113). Updated 2024. Available at: nice.org.uk
- 5 World Health Organization (WHO). WHO Model List of Essential Medicines – 23rd List, 2023. Geneva: World Health Organization; 2023.
- 6 British National Formulary (BNF). Pregabalin. National Institute for Health and Care Excellence. Updated 2025. Available at: bnf.nice.org.uk
- 7 Derry S, Bell RF, Straube S, Wiffen PJ, Aldington D, Moore RA. Pregabalin for neuropathic pain in adults. Cochrane Database of Systematic Reviews. 2019;1(1):CD007076. doi:10.1002/14651858.CD007076.pub3
- 8 Feltner DE, Crockatt JG, Dubovsky SJ, et al. A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder. J Clin Psychopharmacol. 2003;23(3):240-249.
- 9 Evoy KE, Morrison MD, Saklad SR. Abuse and Misuse of Pregabalin and Gabapentin. Drugs. 2017;77(4):403-426. doi:10.1007/s40265-017-0700-x
- 10 Patorno E, Bateman BT, Huybrechts KF, et al. Pregabalin use in pregnancy and the risk of congenital malformations. Neurology. 2020;95(7):e844-e855.
Editorial Team
Written by the iMedic Medical Editorial Team, comprising licensed specialist physicians in clinical pharmacology, neurology, psychiatry, and pain medicine with documented academic backgrounds and clinical experience.
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