Rosuvastatin and Ticagrelor: Drug Interaction Guide

Quick answer: Rosuvastatin and Ticagrelor have a minor interaction — typically manageable with awareness.

Interaction severity: Minor — typically manageable

How Rosuvastatin interacts with Ticagrelor

Ticagrelor may inhibit breast cancer resistance protein and other transport pathways involved in rosuvastatin disposition. This can modestly increase rosuvastatin exposure.

What you should do

Usually no routine dose change is required. Monitor for muscle symptoms, particularly with high-dose rosuvastatin or additional myopathy risk factors.

Key facts

Severity

Minor — typically manageable

Mechanism

Ticagrelor may inhibit breast cancer resistance protein and other transport pathways involved in rosuvastatin dispositio...

Action

Usually no routine dose change is required. Monitor for muscle symptoms, particularly with high-dose rosuvastatin or add...

Important medical disclaimer: This page provides educational information about drug interactions for general reference. It is not a substitute for professional medical advice, diagnosis, or treatment. Always discuss your specific medications with a qualified healthcare provider before starting, stopping, or changing any treatment. About our editorial team.

Frequently asked questions

Can I take Rosuvastatin and Ticagrelor together?

Usually yes, with awareness. Usually no routine dose change is required. Monitor for muscle symptoms, particularly with high-dose rosuvastatin or additional myopathy risk factors.

What is the severity of this interaction?

The interaction between Rosuvastatin and Ticagrelor is classified as Minor — typically manageable. Ticagrelor may inhibit breast cancer resistance protein and other transport pathways involved in rosuvastatin disposition. This can modestly increase rosuvastatin exposure.

What should I do if I'm prescribed both?

Usually no routine dose change is required. Monitor for muscle symptoms, particularly with high-dose rosuvastatin or additional myopathy risk factors. Always consult your prescribing clinician — do not stop or change medications without medical guidance.

Last reviewed: by iMedic Medical Editorial Team. Our editorial process.