Levothyroxine and Iron: Drug Interaction Guide
Quick answer: This combination requires caution. Levothyroxine and Iron can be used together with adjustments and monitoring.
How Levothyroxine interacts with Iron
Iron binds levothyroxine in gut, reducing absorption.
What you should do
Separate doses by at least 4 hours.
Key facts
Severity
Moderate — caution required
Mechanism
Iron binds levothyroxine in gut, reducing absorption.
Action
Separate doses by at least 4 hours.
Important medical disclaimer: This page provides educational information about drug interactions for general reference. It is not a substitute for professional medical advice, diagnosis, or treatment. Always discuss your specific medications with a qualified healthcare provider before starting, stopping, or changing any treatment. About our editorial team.
Frequently asked questions
Can I take Levothyroxine and Iron together?
With caution. Separate doses by at least 4 hours.
What is the severity of this interaction?
The interaction between Levothyroxine and Iron is classified as Moderate — caution required. Iron binds levothyroxine in gut, reducing absorption.
What should I do if I'm prescribed both?
Separate doses by at least 4 hours. Always consult your prescribing clinician — do not stop or change medications without medical guidance.
Last reviewed: by iMedic Medical Editorial Team. Our editorial process.