Atovaquone and Metoclopramide: Drug Interaction Guide
Quick answer: This combination requires caution. Atovaquone and Metoclopramide can be used together with adjustments and monitoring.
How Atovaquone interacts with Metoclopramide
Metoclopramide can reduce plasma atovaquone concentrations, probably by altering gastrointestinal absorption and transit.
What you should do
Avoid routine coadministration when effective atovaquone exposure is essential, or use an alternative antiemetic and monitor clinical response.
Key facts
Severity
Moderate — caution required
Mechanism
Metoclopramide can reduce plasma atovaquone concentrations, probably by altering gastrointestinal absorption and transit...
Action
Avoid routine coadministration when effective atovaquone exposure is essential, or use an alternative antiemetic and mon...
Frequently asked questions
Can I take Atovaquone and Metoclopramide together?
With caution. Avoid routine coadministration when effective atovaquone exposure is essential, or use an alternative antiemetic and monitor clinical response.
What is the severity of this interaction?
The interaction between Atovaquone and Metoclopramide is classified as Moderate — caution required. Metoclopramide can reduce plasma atovaquone concentrations, probably by altering gastrointestinal absorption and transit.
What should I do if I'm prescribed both?
Avoid routine coadministration when effective atovaquone exposure is essential, or use an alternative antiemetic and monitor clinical response. Always consult your prescribing clinician — do not stop or change medications without medical guidance.
Last reviewed: by iMedic Medical Editorial Team. Our editorial process.