Acetylsalicylic Acid and Enalapril: Drug Interaction Guide
Quick answer: Acetylsalicylic Acid and Enalapril have a minor interaction — typically manageable with awareness.
How Acetylsalicylic Acid interacts with Enalapril
Analgesic doses of acetylsalicylic acid inhibit renal cyclooxygenase and prostaglandin synthesis, which can modestly reduce the antihypertensive and renal haemodynamic effects of enalapril.
What you should do
Low antiplatelet doses are generally acceptable. Monitor blood pressure and renal function if higher anti-inflammatory doses are used.
Key facts
Severity
Minor — typically manageable
Mechanism
Analgesic doses of acetylsalicylic acid inhibit renal cyclooxygenase and prostaglandin synthesis, which can modestly red...
Action
Low antiplatelet doses are generally acceptable. Monitor blood pressure and renal function if higher anti-inflammatory d...
Frequently asked questions
Can I take Acetylsalicylic Acid and Enalapril together?
Usually yes, with awareness. Low antiplatelet doses are generally acceptable. Monitor blood pressure and renal function if higher anti-inflammatory doses are used.
What is the severity of this interaction?
The interaction between Acetylsalicylic Acid and Enalapril is classified as Minor — typically manageable. Analgesic doses of acetylsalicylic acid inhibit renal cyclooxygenase and prostaglandin synthesis, which can modestly reduce the antihypertensive and renal haemodynamic effects of enalapril.
What should I do if I'm prescribed both?
Low antiplatelet doses are generally acceptable. Monitor blood pressure and renal function if higher anti-inflammatory doses are used. Always consult your prescribing clinician — do not stop or change medications without medical guidance.
Last reviewed: by iMedic Medical Editorial Team. Our editorial process.