Travel Medicine Kit: Essential Medications & First Aid Guide

Medically reviewed | Last reviewed: | Evidence level: 1A
A well-prepared travel medicine kit is essential for safe international travel. Whether you're heading to a tropical destination, backpacking through remote areas, or taking a family vacation, having the right medications and first aid supplies can prevent minor health issues from becoming major problems. This comprehensive guide covers everything you need to pack, from basic pain relievers to destination-specific medications.
📅 Updated:
⏱️ Reading time: 12 minutes
Written and reviewed by iMedic Medical Editorial Team | Specialists in travel medicine

📊 Quick facts about travel medicine kits

Preparation time
4-8 weeks
before departure
Traveler's diarrhea
30-70%
of travelers affected
Extra medication
+50%
more than needed
DEET concentration
20-50%
for insect repellent
Sunscreen SPF
30+
minimum recommended
ICD-10 Code
Z71.84
Travel health advice

💡 Key takeaways for your travel medicine kit

  • Start preparing 4-8 weeks before travel: This allows time for vaccinations and obtaining prescription medications
  • Keep medications in original containers: This prevents problems at customs and ensures you have dosing information
  • Pack medications in carry-on luggage: Never put essential medications in checked baggage that could be lost or delayed
  • Bring more than you need: Pack at least 50% extra of all prescription medications for unexpected travel delays
  • Research destination-specific requirements: Some countries have restrictions on certain medications that are legal elsewhere
  • Get a doctor's letter: For prescription medications, carry documentation explaining your medical conditions and treatments

Why Do You Need a Travel Medicine Kit?

A travel medicine kit ensures you have immediate access to essential medications and first aid supplies when healthcare may be unavailable, expensive, or unfamiliar. Studies show that 30-70% of international travelers experience some health issue during their trip, most commonly traveler's diarrhea, motion sickness, or minor injuries.

Traveling to unfamiliar destinations presents unique health challenges that a well-prepared medicine kit can help address. When you're far from home, finding specific medications can be difficult, especially if product names differ between countries or if the quality and authenticity of local medications are uncertain. Language barriers can make it challenging to communicate your needs at foreign pharmacies, and some destinations may have limited access to healthcare facilities altogether.

The World Health Organization reports that health problems affect a significant proportion of travelers, with the risk varying based on destination, duration of travel, and traveler characteristics. Common issues include gastrointestinal problems, respiratory infections, skin conditions, and injuries from accidents. Having appropriate medications readily available means you can address these problems quickly, often preventing them from worsening and potentially ruining your trip.

Beyond treating illnesses, a travel medicine kit serves an important preventive function. Insect repellent protects against mosquito-borne diseases like malaria, dengue, and Zika virus. Sunscreen prevents painful sunburns and long-term skin damage. Water purification tablets can make questionable water sources safe to drink. These preventive measures are often more effective and less expensive than treating the conditions they prevent.

Economic and Practical Benefits

Medical care abroad can be extremely expensive, particularly in countries where tourists are charged premium rates or where evacuation to appropriate facilities might be necessary. Having basic medications and first aid supplies can help you manage minor health issues without incurring significant medical costs. Additionally, time spent seeking medical care is time away from your planned activities, making self-treatment of minor issues a practical choice.

What Are the Essential Medications for Travel?

Essential travel medications include pain relievers (paracetamol/acetaminophen and ibuprofen), antihistamines for allergies, anti-diarrheal medication (loperamide), oral rehydration salts, motion sickness tablets, antacids, decongestants, and cough medicine. These cover the most common travel health complaints and are generally available over-the-counter.

Building an effective travel medicine kit starts with understanding which medications address the most common travel health problems. The foundation of any kit should include medications you might need regardless of your destination, with additional items added based on your specific travel plans. It's important to choose medications you've used before and know you tolerate well, as discovering a new medication allergy while traveling can be dangerous.

Pain management is typically the most frequent need while traveling. Paracetamol (acetaminophen) is effective for headaches, general pain, and fever reduction. Ibuprofen or another non-steroidal anti-inflammatory drug (NSAID) provides additional options for pain with inflammation, such as muscle strains or dental pain. Having both allows you to alternate them for more severe pain or fever while avoiding excessive doses of either medication.

Antihistamines serve multiple purposes in a travel kit. They treat allergic reactions to foods, insect stings, or environmental allergens. Non-drowsy formulations like cetirizine or loratadine are preferred for daytime use, while diphenhydramine (which causes drowsiness) can double as a sleep aid for jet lag. Antihistamines can also help reduce motion sickness symptoms and relieve itching from insect bites.

Gastrointestinal Medications

Digestive issues are among the most common travel health problems. Traveler's diarrhea affects 30-70% of travelers to high-risk destinations, making anti-diarrheal medication essential. Loperamide (Imodium) reduces intestinal motility and can provide relief when bathroom access is limited, such as during long bus rides. However, it should not be used if diarrhea is accompanied by fever or bloody stools, which may indicate a more serious infection requiring medical attention.

Oral rehydration salts (ORS) are critical for treating dehydration from diarrhea, vomiting, or excessive heat exposure. Dehydration is the main danger from diarrheal illness, and ORS solutions are more effective than water alone because they replace lost electrolytes. Pre-mixed sachets are convenient for travel and can be dissolved in bottled water.

Antacids or acid-reducing medications treat heartburn and indigestion, which can be triggered by unfamiliar foods, different eating schedules, or stress. Options include calcium carbonate tablets for quick relief or H2 blockers like famotidine for longer-lasting acid suppression.

Essential over-the-counter medications for your travel kit
Medication Purpose Typical Dose Notes
Paracetamol/Acetaminophen Pain, fever 500-1000mg every 4-6 hours Max 4g/day; avoid with liver problems
Ibuprofen Pain, inflammation, fever 200-400mg every 4-6 hours Take with food; avoid if history of stomach ulcers
Loperamide Diarrhea 2mg after loose stool, then 2mg as needed Max 16mg/day; stop if fever or bloody stools
Cetirizine/Loratadine Allergies, itching 10mg once daily Non-drowsy; good for daytime use
Oral Rehydration Salts Dehydration 1 packet per liter of water Essential for treating diarrhea/vomiting
Dimenhydrinate Motion sickness 50-100mg every 4-6 hours Take 30 min before travel; causes drowsiness

How Should You Handle Prescription Medications?

Prescription medications should be kept in original containers with pharmacy labels, accompanied by a doctor's letter explaining your conditions and treatments. Pack at least 50% more medication than needed for your trip duration, split between carry-on and checked luggage. Research destination regulations, as some medications legal at home may be restricted elsewhere.

Managing prescription medications for international travel requires careful planning and documentation. Different countries have varying regulations about what medications can be imported, and some substances that are legal in your home country may be controlled or prohibited elsewhere. Preparing properly ensures you can access your necessary medications throughout your trip without legal complications or supply issues.

The foundation of prescription medication travel is maintaining original pharmacy packaging. Containers with your name, the prescribing doctor's information, pharmacy details, and dispensing instructions provide crucial documentation that the medications are legally prescribed to you. Customs officials in many countries view loose pills in unlabeled containers with suspicion, potentially leading to confiscation or legal problems.

Before traveling, request a letter from your prescribing physician that includes your medical diagnosis, the medications prescribed (using both brand and generic names), dosages, and a statement that these medications are medically necessary for you. This letter serves as additional documentation at border crossings and can be invaluable if you need medical care abroad, as local doctors will understand your baseline health status and current treatments.

Calculating Medication Quantities

Always bring more medication than your trip duration would normally require. The general recommendation is to pack at least 50% extra beyond what you'll need for the planned trip length. This buffer accounts for unexpected travel delays, lost luggage, medication dropped or damaged, or extended stays due to weather, political situations, or other circumstances. For critical medications like insulin, heart medications, or psychiatric drugs, consider bringing even more.

Split your medication supply between carry-on and checked luggage. Keep enough in your carry-on to last the entire trip (in case checked bags are lost), while storing backup supplies in checked bags. This redundancy protects against the common problem of lost luggage while ensuring you always have access to necessary medications.

Controlled Substances Require Extra Preparation

If you take controlled substances (opioid pain medications, ADHD medications, certain anxiety medications, or sleep aids), research destination regulations carefully. Some countries have complete bans on certain substances regardless of prescription status. Contact the embassy or consulate of your destination country for specific requirements. You may need additional documentation, import permits, or to carry medications in their original sealed packaging.

Refilling Prescriptions Abroad

In some cases, you may need to refill prescriptions while traveling. Carry copies of your prescriptions (not just the medication labels) that include the generic drug name, as brand names vary internationally. Be aware that many medications available over-the-counter in some countries require prescriptions in others, and vice versa. If you need to see a local doctor for a prescription refill, your letter from your home physician will help them understand your medical history.

What First Aid Supplies Should You Include?

Essential first aid supplies include various sizes of adhesive bandages, sterile gauze pads and rolls, medical tape, antiseptic wipes or solution, antibiotic ointment, tweezers, small scissors, digital thermometer, elastic bandage for sprains, blister treatment, and instant cold packs. For remote destinations, add sterile needle kits and wound closure strips.

First aid supplies complement your medications by providing the tools to treat minor injuries and prevent infections. The contents of your first aid kit should reflect your travel style, destination, and planned activities. A city-based business trip requires less extensive supplies than a wilderness trekking adventure, but certain basics are valuable for any traveler.

Wound care forms the core of first aid supplies. Minor cuts, scrapes, and blisters are common travel injuries. Adhesive bandages in various sizes handle most small wounds, while sterile gauze pads and rolls manage larger injuries. Medical tape secures dressings and can be used for other purposes like taping blisters or securing splints. Antiseptic wipes or solution (povidone-iodine or chlorhexidine) clean wounds before dressing, crucial for preventing infection especially in tropical climates where wounds heal more slowly.

Antibiotic ointment (such as bacitracin or mupirocin) applied to clean wounds before bandaging helps prevent bacterial infection. In warm, humid climates where bacterial growth accelerates, keeping wounds clean and dressed with antibiotic ointment is particularly important. Watch for signs of infection (increasing redness, swelling, warmth, pus, or red streaks spreading from the wound) that indicate need for medical attention.

Tools and Instruments

Tweezers are invaluable for removing splinters, thorns, ticks, and bee stingers. Quality stainless steel tweezers with pointed tips provide better grip than cheaper alternatives. Small scissors cut medical tape, bandages, and moleskin for blister treatment. A digital thermometer helps assess whether you have a fever, which may indicate infection requiring medical attention—important information when deciding whether to seek care abroad.

An elastic bandage (ACE bandage) supports sprained joints and can compress swelling from injuries. It's also useful for securing ice packs or as an improvised sling. Blister treatment supplies are essential if you'll be doing significant walking. Moleskin or specialized blister bandages protect developing hot spots and cushion existing blisters, preventing the painful condition that can sideline travelers.

Advanced Supplies for Remote Travel

Travelers venturing to areas with limited medical facilities should consider additional supplies. A sterile needle and syringe kit ensures you have access to sterile injection equipment if you need medical care in areas where needle reuse is a concern. These kits typically include needles, syringes, sutures, and other supplies with a doctor's certificate explaining their purpose.

Wound closure strips (Steri-Strips) can close minor wounds that might otherwise require stitches, useful when evacuation to medical care would take time. An emergency blanket (space blanket) weighs almost nothing but provides significant warmth in emergencies. SAM splints or similar moldable splints allow temporary stabilization of fractures or severe sprains during transport to medical care.

What Medications Do You Need for Specific Destinations?

Tropical and developing-world destinations require additional medications including antimalarials (if recommended), insect repellent with 20-50% DEET, water purification tablets, and broad-spectrum antibiotics for traveler's diarrhea. High-altitude destinations need acetazolamide for altitude sickness prevention. Sun-intensive destinations require high-SPF sunscreen and aloe vera for burns.

Your travel destination significantly influences what medications you should pack beyond the basics. Different regions present different health risks based on infectious disease patterns, climate, altitude, and healthcare infrastructure availability. Consulting a travel health specialist 4-8 weeks before departure allows time for vaccinations and obtaining appropriate prescription medications.

Tropical Destinations

Travel to tropical regions, particularly in Africa, South Asia, Central and South America, and Southeast Asia, introduces risks from mosquito-borne diseases. Antimalarial medication is essential for many destinations where malaria is endemic. The choice of antimalarial (atovaquone-proguanil, doxycycline, or mefloquine) depends on your destination's resistance patterns, your personal health history, and factors like trip duration. Some antimalarials must be started before arrival and continued after leaving the malaria zone.

Insect repellent containing DEET (20-50% concentration) or picaridin provides crucial protection against mosquitoes, ticks, and other biting insects. DEET remains the gold standard with decades of safety data, though picaridin is an effective alternative for those who prefer it. Apply repellent to exposed skin and clothing, reapplying as directed. Permethrin-treated clothing provides additional protection, especially for wilderness travelers.

Water purification tablets (iodine or chlorine-based) allow you to safely drink questionable water when bottled water isn't available. While buying bottled water is generally preferable, purification tablets serve as backup for emergencies or remote areas. UV water purifiers and filtering bottles offer more sustainable alternatives for longer trips.

Traveler's Diarrhea Management

For high-risk destinations, consider carrying a prescription antibiotic for self-treatment of traveler's diarrhea. Azithromycin is often prescribed because it's effective against most diarrhea-causing bacteria and is taken as a short course. Ciprofloxacin was formerly the standard but increasing bacterial resistance has reduced its reliability in some regions. Your travel health provider can recommend the most appropriate antibiotic for your destination.

When to Use Antibiotics for Diarrhea

Antibiotics are typically recommended when diarrhea is moderate to severe (more than 4 loose stools daily, fever, bloody stools, or severe cramps). Mild diarrhea often resolves with fluid replacement and time. Using antibiotics unnecessarily contributes to antibiotic resistance and can cause side effects. Consult your travel health provider for guidance on when self-treatment is appropriate.

High-Altitude Destinations

Travel to high-altitude destinations (above 2,500 meters/8,000 feet) carries risk of altitude sickness. Acetazolamide (Diamox) helps prevent and treat altitude sickness by speeding acclimatization. It's typically started 1-2 days before ascending to high altitude and continued for 2-3 days at high altitude. Side effects include tingling in fingers and toes and altered taste of carbonated beverages. Proper acclimatization—ascending gradually and allowing time for adjustment—remains the primary prevention strategy.

What Documentation Do You Need for Your Medications?

Essential documentation includes a doctor's letter listing diagnoses and medications (with generic names), copies of all prescriptions, original pharmacy labels on medication containers, vaccination records, travel insurance information with medical coverage details, and your doctor's contact information. Keep digital copies in email or cloud storage as backup.

Proper documentation can prevent problems at border crossings, help you receive appropriate medical care abroad, and provide peace of mind. While requirements vary by country and medication type, comprehensive documentation protects you in most situations and demonstrates good faith to customs officials.

A physician's letter is the most important piece of documentation. This letter should be on official letterhead and include your name, medical conditions, medications prescribed (both brand and generic names), dosages, and a statement that these medications are medically necessary. The letter should be signed, dated, and include the physician's license number and contact information. Consider having it translated into the primary language of your destination country.

Carry copies of prescriptions separate from your medications. These can help if you need refills abroad or if your medications are questioned at customs. The generic drug name is particularly important since brand names vary internationally. Some pharmacies can provide computer printouts of your prescription history that document your medications comprehensively.

Digital Backup

Create digital copies of all medication documentation and store them in multiple accessible locations. Email copies to yourself, upload to cloud storage, and keep photos on your phone. If physical documents are lost or damaged, digital backups ensure you still have proof of your prescriptions. Additionally, digital copies can be easily shared with medical providers abroad if needed.

Keep a medication list in your wallet or on your phone that includes all current medications, dosages, allergies, and emergency contact information. This information is invaluable if you need emergency medical care and cannot communicate directly with providers. Medical alert cards or apps can organize this information in a format easily understood by healthcare providers.

How Should You Pack Your Travel Medicine Kit?

Use a waterproof, durable bag or hard case for your medicine kit. Pack medications in carry-on luggage, keeping them organized by type. Create an inventory list of contents. Check expiration dates before each trip and replace expired items. Store the kit in a cool, dry location and avoid extreme temperatures during travel.

How you pack and store your travel medicine kit affects both its accessibility and the effectiveness of its contents. Proper organization ensures you can find what you need quickly, while appropriate storage conditions maintain medication potency throughout your trip.

Choose a waterproof container for your medicine kit. Options range from waterproof bags to hard plastic cases, depending on your travel style. The container should be large enough to hold all supplies while remaining compact enough to pack easily. Clear pouches or compartments within the kit help organize different types of supplies—medications, first aid, and tools—for quick access.

Pack medications in carry-on luggage whenever flying. Checked bags can be lost, delayed, or exposed to extreme temperatures in cargo holds that may damage medications. Your carry-on supply should be sufficient for your entire trip, with backup supplies in checked luggage as a secondary safety measure. Keep medications accessible for security screening—you may need to present them for inspection.

Medication Storage Considerations

Most medications should be stored at room temperature (15-25°C/59-77°F) and protected from moisture and direct sunlight. Some medications, particularly certain antibiotics and insulin, require refrigeration. If you're traveling with temperature-sensitive medications, use insulated bags with ice packs (following airline regulations) or portable medication coolers designed for travel.

Check expiration dates before every trip and replace expired medications. While some medications remain effective past their expiration date, potency can decrease significantly, and some medications (like liquid antibiotics or epinephrine auto-injectors) can become unsafe after expiration. Build a habit of reviewing your travel medicine kit regularly, replacing used or expired items.

Creating an Inventory List

Maintain a written inventory of your travel medicine kit contents, including medication names, quantities, expiration dates, and dosing instructions. This list helps you quickly check that everything is packed and serves as documentation if customs officials have questions. Update the list whenever you use or replace items. Keep a copy with your travel documents and another at home.

What Special Considerations Apply for Children and Elderly Travelers?

Children require age-appropriate medication formulations (liquid suspensions, chewables), pediatric dosing guides, and child-specific items like infant fever reducers and teething gel. Elderly travelers may need larger medication supplies, specialized equipment, medical device supplies, and documentation of multiple health conditions. Both groups benefit from pre-travel medical consultations.

Travelers at the extremes of age—children and elderly individuals—have unique medical needs that require special consideration when preparing a travel medicine kit. Standard adult medications may be inappropriate, and additional supplies may be necessary to address age-specific health concerns.

Traveling with Children

Children require age-appropriate medication formulations. Liquid suspensions are easier to administer to young children than tablets, and many medications come in special pediatric strengths. Common essentials for traveling with children include pediatric fever reducer/pain reliever (acetaminophen or ibuprofen suspension), antihistamine drops or syrup, oral rehydration solution packets, and diaper rash cream for infants.

A pediatric dosing guide is essential since children's doses are calculated by weight, which changes frequently. Record your child's current weight and refer to package instructions or your pediatrician's guidance for appropriate doses. Never give adult-strength medications to children without specific guidance from a healthcare provider.

Consider including comfort items that serve medical purposes, such as familiar bandages with favorite characters (encouraging children to accept first aid treatment), fever strips that indicate temperature without requiring thermometer compliance, and distraction items for medical procedures. Teething gel and numbing spray can address oral discomfort that's common during travel.

Traveling with Elderly Family Members

Elderly travelers often take multiple medications for chronic conditions, making organization crucial. Pill organizers with compartments for different times of day help maintain medication schedules across time zones. Ensure all medications are clearly labeled with instructions visible to the user, considering any vision impairments.

Bring additional supplies for any medical devices—extra batteries for hearing aids, backup glasses or contact lenses, extra supplies for CPAP machines, or replacement parts for mobility aids. For travelers with chronic conditions like diabetes, include extra glucose monitoring supplies, backup insulin with cooling storage, and fast-acting glucose for hypoglycemia.

Documentation becomes even more important for elderly travelers with multiple health conditions. A comprehensive medical summary should list all conditions, medications, allergies, and relevant surgical history. Emergency contact information should include primary care physicians and any specialists involved in the traveler's care.

When Should You Seek Medical Care While Traveling?

Seek immediate medical care for high fever (over 39°C/102°F), difficulty breathing, severe chest or abdominal pain, confusion or altered consciousness, severe bleeding, signs of dehydration unresponsive to oral fluids, allergic reactions with swelling or breathing difficulty, or any potentially serious injury. Contact your travel insurance provider for guidance on finding appropriate care.

While a well-prepared travel medicine kit handles many common health issues, some situations require professional medical attention. Recognizing when self-treatment is insufficient can prevent serious complications and potentially save lives. Understanding the local healthcare system before you need it makes emergencies less stressful.

High fever (above 39°C/102°F) lasting more than 24-48 hours or accompanied by severe symptoms warrants medical evaluation. In malaria-endemic areas, any fever within one year of travel should be evaluated for malaria, as the disease can progress rapidly. Fever with rash, stiff neck, severe headache, or confusion may indicate serious infections requiring immediate care.

Respiratory symptoms including difficulty breathing, persistent cough with bloody sputum, or chest pain with breathing should prompt medical evaluation. These may indicate pneumonia, pulmonary embolism (especially after long flights), or other serious conditions. Similarly, severe chest pain or pressure, particularly with shortness of breath, arm pain, or sweating, requires emergency care for possible heart attack.

Gastrointestinal Warning Signs

Diarrhea requiring attention includes bloody stools, fever over 38.5°C/101°F with diarrhea, severe abdominal cramping, diarrhea lasting more than 3-4 days despite treatment, or signs of significant dehydration (dizziness when standing, very dark urine, inability to keep fluids down). While most traveler's diarrhea resolves with supportive care, these warning signs indicate possible bacterial dysentery or other infections needing professional treatment.

Severe dehydration that doesn't improve with oral rehydration requires intravenous fluids. Signs include extreme thirst, very dark or minimal urine output, rapid heartbeat, dizziness or confusion, and dry mouth and skin. Young children and elderly individuals are particularly vulnerable to dehydration complications.

Emergency Warning Signs - Seek Immediate Care
  • Difficulty breathing or shortness of breath
  • Chest pain or pressure
  • Severe allergic reaction (swelling of face/throat, difficulty swallowing)
  • Loss of consciousness or confusion
  • Severe bleeding that won't stop
  • Signs of stroke (facial drooping, arm weakness, speech difficulty)
  • Severe abdominal pain

Find emergency numbers for your destination →

Using Travel Insurance

Contact your travel insurance provider before seeking non-emergency care when possible. Many insurers have 24-hour assistance lines that can direct you to quality medical facilities, arrange direct payment (avoiding large out-of-pocket expenses), and help with language interpretation. Keep your insurance policy details, assistance phone number, and policy number easily accessible.

Frequently Asked Questions About Travel Medicine Kits

Medical References and Sources

This article is based on current medical research and international travel health guidelines. All claims are supported by scientific evidence from peer-reviewed sources.

  1. Centers for Disease Control and Prevention (CDC) (2024). "CDC Yellow Book 2024: Health Information for International Travel." https://wwwnc.cdc.gov/travel/yellowbook/2024 Comprehensive travel health guidelines for healthcare providers and travelers.
  2. World Health Organization (WHO) (2024). "International Travel and Health." WHO Travel Advice Global health recommendations for international travelers.
  3. International Society of Travel Medicine (ISTM) (2024). "Travel Medicine Practice Guidelines." Professional guidelines for travel medicine practitioners.
  4. Steffen R, et al. (2020). "Travelers' diarrhea: A clinical review." JAMA. 324(1):82-90. Evidence-based review of traveler's diarrhea prevention and treatment.
  5. Freedman DO, et al. (2024). "Pre-travel advice: An overview." Travel Medicine and Infectious Disease. Comprehensive review of pre-travel medical consultation recommendations.
  6. Transportation Security Administration (TSA) (2024). "Medications and Medical Equipment." TSA Guidelines Official guidelines for traveling with medications.

Evidence grading: This article uses recommendations from major international health organizations (WHO, CDC, ISTM) and peer-reviewed medical literature. Travel health recommendations are regularly updated based on current disease surveillance and evidence.

⚕️

iMedic Medical Editorial Team

Specialists in travel medicine and infectious diseases

Our Editorial Team

iMedic's medical content is produced by a team of licensed specialist physicians and medical experts with solid academic background and clinical experience. Our editorial team includes:

Travel Medicine Specialists

Licensed physicians specializing in travel medicine with experience in pre-travel consultations and tropical disease prevention.

Infectious Disease Experts

Specialists in infectious diseases with expertise in malaria, traveler's diarrhea, and other travel-related infections.

Emergency Medicine

Emergency physicians with experience in wilderness medicine and medical evacuation considerations.

Medical Review

Independent review panel that verifies all content against international travel health guidelines and current research.

Qualifications and Credentials
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  • Members of ISTM (International Society of Travel Medicine)
  • Documented research background with publications in peer-reviewed journals
  • Continuous education according to WHO and CDC guidelines
  • Follows evidence-based medicine principles

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