Personalized Gait Retraining May Ease Knee

Medically reviewed | Published: | Evidence level: 1A
A randomized trial reported in The Lancet Rheumatology found that personalized foot-angle retraining improved pain and reduced knee loading in adults with mild-to-moderate medial knee osteoarthritis. The findings suggest that a precisely tailored walking change could become a low-risk addition to physical therapy, but it should be guided by clinicians rather than attempted blindly.
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Quick Facts

Trial Size
68 adults
Follow-Up
12 months
Angle Change
5-10 degrees

Can changing the way you walk reduce knee osteoarthritis pain?

Quick answer: A personalized change in foot angle may reduce pain for some people with medial knee osteoarthritis by lowering stress through the inner knee.

Researchers studying medial compartment knee osteoarthritis tested whether small, individualized changes in foot progression angle could reduce the mechanical load that passes through the painful part of the knee. In the randomized controlled trial, participants were assigned either to a personalized gait retraining program or to a sham training approach that kept their natural walking angle.

The intervention was not a generic instruction to turn the toes in or out. Each person first underwent gait testing to identify whether a 5- or 10-degree inward or outward adjustment reduced their knee loading most effectively. That distinction matters because the same walking change can help one patient but fail to reduce stress in another.

How might gait retraining protect knee cartilage?

Quick answer: Gait retraining may help by reducing knee adduction moment, a biomechanical marker linked to load across the inner knee compartment.

Knee osteoarthritis is often treated with exercise, weight management, physical therapy, pain medicines, injections, and eventually joint replacement for advanced disease. The new trial focuses on biomechanics: if walking places less force through the damaged inner compartment, symptoms may improve and cartilage deterioration may slow.

In the study, MRI-based measures suggested less worsening of cartilage microstructure in the gait-retraining group than in the sham group. This does not prove that the method prevents knee replacement or reverses osteoarthritis, but it raises an important possibility: mechanical interventions may be able to change not only pain perception but also the loading environment that contributes to progression.

Should patients try foot-angle changes on their own?

Quick answer: Patients should not make major gait changes without professional guidance because the wrong adjustment could increase knee stress.

The most clinically important message is personalization. The trial used laboratory gait analysis and real-time feedback, not casual advice to walk differently. People with knee pain may also have hip, ankle, balance, spine, or neurologic issues that affect whether a walking change is safe or useful.

For patients, the practical next step is discussion with a physical therapist, sports medicine clinician, or orthopedic specialist familiar with osteoarthritis management. If future studies confirm the results in larger and more diverse groups, wearable sensors and clinic-based gait tools could make this approach easier to deliver outside specialized research laboratories.

Frequently Asked Questions

No. Osteoarthritis-related cartilage damage cannot currently be reliably reversed in routine care. Gait retraining may reduce pain and joint loading for selected patients, but it should be viewed as one part of a broader treatment plan.

The trial focused on people with mild-to-moderate medial compartment knee osteoarthritis who could safely walk on a treadmill and whose knee loading improved during gait testing. Results may not apply to every type or stage of knee arthritis.

No. Evidence-based osteoarthritis care still commonly includes physical activity, strengthening, weight management when appropriate, education, and symptom control. Personalized gait retraining may become an additional option for some patients.

References

  1. Uhlrich SD, Mazzoli V, Silder A, Finlay AK, Kogan F, Gold GE, Delp SL, Beaupre GS, Kolesar JA. Personalised gait retraining for medial compartment knee osteoarthritis: a randomised controlled trial. The Lancet Rheumatology. 2025. doi:10.1016/S2665-9913(25)00151-1.
  2. University of Utah. Scientists discover simple way to relieve arthritis pain without pills or surgery. ScienceDaily. May 22, 2026.
  3. Centers for Disease Control and Prevention. Osteoarthritis. Arthritis. Accessed May 23, 2026.