Medical Oxygen: Can Better Access Strengthen Pandemic

✓ Medically reviewed | Published: | Evidence level: 1A
International pandemic preparedness efforts highlight a fundamental clinical need: reliable medical oxygen. A Lancet Global Health commission published in 2025 estimated that approximately 374 million people need oxygen annually, underscoring why preparedness must include dependable treatment infrastructure.
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✓ Reviewed by iMedic Medical Editorial Team
📄 Public Health

Quick Facts

Estimated Annual Need
374 million people
Estimated Access Gap
5 billion people
Need in Lower-Income Countries
82% of global need

Why does medical oxygen matter for pandemic preparedness?

Quick answer: Reliable oxygen services help hospitals treat dangerously low blood oxygen when respiratory outbreaks increase demand.

The WHO announcement behind the supplied pandemic-agreement headline dates to May 2024, when negotiations were continuing. The World Health Assembly subsequently adopted the agreement in May 2025. These developments frame a practical preparedness challenge: hospitals need treatment capacity alongside systems for detecting emerging infections. Oxygen access is one concrete measure of that capacity. [WHO negotiation announcement](https://www.who.int/news/item/10-05-2024-governments-agree-to-continue-their-steady-progress-on-proposed-pandemic-agreement-ahead-of-the-world-health-assembly), [WHO adoption announcement](https://www.who.int/news/item/20-05-2025-world-health-assembly-adopts-historic-pandemic-agreement-to-make-the-world-more-equitable-and-safer-from-future-pandemics).

Severe respiratory illness can cause hypoxemia, meaning abnormally low oxygen levels in the blood. Supplemental oxygen addresses this dangerous consequence while clinicians treat the underlying illness. WHO guidance emphasizes identifying affected patients, delivering an uninterrupted supply and monitoring their response. These capabilities also support everyday care, including children hospitalized with severe pneumonia, making investment useful between outbreaks as well as during them. [WHO oxygen therapy manual](https://www.who.int/publications/i/item/9789241549554).

How large is the global medical oxygen access gap?

Quick answer: A major commission estimated that about 5 billion people lack access to affordable, high-quality medical oxygen services.

The 2025 Lancet Global Health Commission on medical oxygen security estimated annual treatment needs at approximately 374 million people. About 82% of that need was in low- and middle-income countries. Its separate estimate of a 5 billion-person access gap describes people without adequate access to affordable, high-quality services; it does not mean that all those people currently require oxygen. These are population estimates assembled from available evidence, rather than a direct count of individual patients. [Lancet Global Health commission](https://pmc.ncbi.nlm.nih.gov/articles/PMC11865010/).

The clinical demand extends beyond infectious disease to surgery, injuries, newborn care and selected chronic respiratory conditions. The commission argues that equipment deliveries alone cannot establish dependable treatment: production, distribution, clinical use, financing and maintenance must function together. The implication for preparedness is practical. A hospital's ability to obtain oxygen and deliver it consistently matters more than whether a machine appears on its equipment inventory. [Commission findings and recommendations](https://pmc.ncbi.nlm.nih.gov/articles/PMC11865010/).

What makes an oxygen service reliable and safe?

Quick answer: Effective services combine a dependable supply with appropriate delivery equipment, trained staff, patient monitoring and sustained maintenance.

WHO describes oxygen provision as a connected system covering production, storage, distribution, delivery and quality control. At the bedside, pulse oximetry helps identify low blood oxygen and monitor treatment. Staff must also select suitable equipment and reassess patients as their condition changes. Medical oxygen has defined quality requirements, so supply planning includes assurance that the gas meets standards for clinical use. [WHO oxygen questions and answers](https://www.who.int/news-room/questions-and-answers/item/oxygen).

Keeping those services operational requires continuing funding and measurable goals. WHO's national oxygen planning guidance, published in February 2025, covers assessment of existing services, implementation, financing and evaluation. Applied to hospital planning, this approach means identifying supply interruptions, budgeting for maintenance and checking whether patients actually receive the treatment they need. The practical lesson is that procurement should be followed by ongoing assessment of service performance. [WHO national oxygen planning guidance](https://www.who.int/publications/i/item/9789240106512).

Frequently Asked Questions

No. Clinicians assess blood oxygen levels and the patient's overall condition to determine whether oxygen is needed. Pulse oximetry helps detect hypoxemia and monitor treatment. Oxygen supports patients with inadequate oxygenation while the underlying illness receives appropriate care. [WHO oxygen therapy manual](https://www.who.int/publications/i/item/9789241549554).

Yes. WHO warns that prolonged exposure to very high supplemental oxygen levels can cause harm, particularly in premature or low-birth-weight babies. Healthcare professionals should adjust and monitor treatment according to the patient's condition and relevant clinical guidance. [WHO oxygen safety guidance](https://www.who.int/news-room/questions-and-answers/item/oxygen).

References

  1. World Health Organization. Governments agree to continue their steady progress on proposed pandemic agreement ahead of the World Health Assembly. 10 May 2024. https://www.who.int/news/item/10-05-2024-governments-agree-to-continue-their-steady-progress-on-proposed-pandemic-agreement-ahead-of-the-world-health-assembly
  2. World Health Organization. World Health Assembly adopts historic Pandemic Agreement to make the world more equitable and safer from future pandemics. 20 May 2025. https://www.who.int/news/item/20-05-2025-world-health-assembly-adopts-historic-pandemic-agreement-to-make-the-world-more-equitable-and-safer-from-future-pandemics
  3. Reducing global inequities in medical oxygen access: the Lancet Global Health Commission on medical oxygen security. The Lancet Global Health. 2025;13(3):e528–e584. doi:10.1016/S2214-109X(24)00496-0. https://pmc.ncbi.nlm.nih.gov/articles/PMC11865010/
  4. World Health Organization. Oxygen therapy for children: A manual for health workers. 2016. https://www.who.int/publications/i/item/9789241549554
  5. World Health Organization. Oxygen: Questions and answers. 10 October 2024. https://www.who.int/news-room/questions-and-answers/item/oxygen
  6. World Health Organization. National medical oxygen scale-up plan: Development guidance. 5 February 2025. https://www.who.int/publications/i/item/9789240106512