Knee Arthritis: Can Changing Your Walking Angle Ease

✓ Medically reviewed | Published: | Evidence level: 1A
A randomized trial published in The Lancet Rheumatology in 2025 found that personalized walking adjustments reduced knee osteoarthritis pain more than sham training over one year. A cartilage imaging finding was also encouraging, but the research does not establish that the approach prevents joint replacement.
📅 Published:
✓ Reviewed by iMedic Medical Editorial Team
📄 Research

Quick Facts

Trial Size
68 adults
Follow-Up
1 year
Initial Training
6 weekly sessions

What did the knee arthritis walking trial find?

Quick answer: Personalized gait retraining produced greater pain relief than sham training after one year.

The randomized study compared tailored foot-angle changes with training that reinforced each participant's usual walking angle. On a zero-to-10 pain scale, the personalized group improved by an additional 1.2 points compared with the control group. This was an average benefit, rather than a guaranteed response for every patient. The trial did not directly compare gait retraining with medication. [Published trial](https://pubmed.ncbi.nlm.nih.gov/40816302/).

One MRI measure of cartilage microstructure favored the intervention, while another did not differ significantly between groups. That supports further investigation of possible cartilage protection; it does not demonstrate cartilage regrowth. No severe adverse events were reported, although two intervention participants and one control participant withdrew because knee pain increased. [Trial manuscript](https://mobl.mech.utah.edu/wp-content/uploads/2025/08/UhlrichMazzoli_LancetRheum_AcceptedManuscript.pdf).

How can changing your foot angle reduce knee pain?

Quick answer: An individually selected foot angle can redistribute forces away from the affected inner part of the knee.

The direction your toes point changes how forces pass through your knee during each step. Researchers used motion-capture cameras and a treadmill that measured forces to assess small inward and outward adjustments. The useful direction differed between people: a movement that reduced loading for one person could increase it for another. Participants practiced with vibration feedback during six weekly sessions, followed by regular practice outside the laboratory. [Stanford research report](https://news.stanford.edu/stories/2025/08/gait-retraining-knee-osteoarthritis-cartilage-damage-treatment-walking).

Selection was central to the experiment. The registered eligibility criteria required arthritis concentrated in the inner knee, the ability to walk without an aid, and a measurable reduction in knee loading when foot angle changed. People planning knee replacement within the following year were excluded. These restrictions mean the findings cannot automatically be extended to advanced arthritis, other patterns of knee damage, or everyone who experiences knee pain. [Trial registration](https://clinicaltrials.stanford.edu/trials/l/NCT02767570.html).

Should people with knee arthritis change how they walk?

Quick answer: Discuss gait assessment with a physiotherapist rather than choosing an inward or outward foot angle yourself.

The intervention depended on measuring an individual's response and providing repeated feedback. Simply copying a walking style does not reproduce that process. Stanford's report identified the cost and complexity of laboratory assessment as barriers to wider delivery. Researchers are investigating simpler tools, but the trial alone cannot establish that a consumer app or shoe provides equivalent treatment. [Stanford research report](https://news.stanford.edu/stories/2025/08/gait-retraining-knee-osteoarthritis-cartilage-damage-treatment-walking).

Established care remains useful while this approach develops. NICE recommends exercise tailored to the person, including strengthening and aerobic activity, alongside weight-management support when appropriate. Topical anti-inflammatory medication can support symptom control when needed. Joint replacement assessment remains appropriate when symptoms substantially impair quality of life and nonsurgical treatment is ineffective or unsuitable. Gait retraining should be considered within an individualized treatment discussion. [NICE osteoarthritis recommendations](https://www.nice.org.uk/guidance/NG226/chapter/recommendations).

Frequently Asked Questions

The trial did not establish cartilage regrowth. Its MRI findings suggest a possible protective effect that needs further investigation.

There is no universal direction. Researchers selected the adjustment using measurements of each person's knee loading.

The trial compared personalized walking with sham training, not painkillers. It cannot establish superiority to medication.

Usually, no. NICE recommends tailored therapeutic exercise. A physiotherapist can help adapt activity to your symptoms and physical abilities.

That remains uncertain. The trial excluded people planning replacement within a year, so its results should not be used to postpone an otherwise appropriate surgical assessment.

References

  1. Uhlrich SD, et al. Personalised gait retraining for medial compartment knee osteoarthritis: a randomised controlled trial. The Lancet Rheumatology. 2025;7(10):e708–e718. doi:10.1016/S2665-9913(25)00151-1. [PubMed record](https://pubmed.ncbi.nlm.nih.gov/40816302/).
  2. Stanford Report. Study reveals gait retraining could help treat knee osteoarthritis. August 12, 2025. [Research report](https://news.stanford.edu/stories/2025/08/gait-retraining-knee-osteoarthritis-cartilage-damage-treatment-walking).
  3. Stanford Clinical Trials. Personalized Gait Training With Feedback to Reduce Knee Pain From Osteoarthritis. NCT02767570. [Eligibility and registration](https://clinicaltrials.stanford.edu/trials/l/NCT02767570.html).
  4. National Institute for Health and Care Excellence. Osteoarthritis in over 16s: diagnosis and management. NICE guideline NG226. 2022. [Recommendations](https://www.nice.org.uk/guidance/NG226/chapter/recommendations).