Osteoarthritis Risk: Can Better Heart Health Help?

✓ Medically reviewed | Published: | Evidence level: 1A
Better cardiovascular health was associated with lower osteoarthritis risk in a large UK Biobank study published in RMD Open. The findings are observational; established guidance already supports tailored exercise and appropriate weight management for people with osteoarthritis.
📅 Published:
✓ Reviewed by iMedic Medical Editorial Team
📄 Cardiovascular Health

Quick Facts

Study Participants
102,794 adults
Median Follow-up
13.1 years
New Osteoarthritis Cases
15,984 cases

What did the heart health and osteoarthritis study find?

Quick answer: Higher cardiovascular health scores were associated with fewer osteoarthritis diagnoses, although the study cannot prove prevention.

The study, published on May 13, 2026, found a 32% lower adjusted hazard of osteoarthritis among participants in the highest quarter of cardiovascular health scores compared with the lowest quarter. This relative comparison does not mean 32 fewer diagnoses per 100 people. [RMD Open study](https://rmdopen.bmj.com/content/12/2/e006881).

Participants were observed rather than randomly assigned an intervention, leaving room for other differences to influence the results. Exploratory blood-protein analyses suggested metabolic and inflammatory connections, but did not establish biological mechanisms or a validated screening test. [Study findings](https://rmdopen.bmj.com/content/12/2/e006881).

Why consider heart and joint health together?

Quick answer: Joint health and cardiovascular health share practical priorities, including physical activity and support with weight management.

Osteoarthritis affects the entire joint, including surrounding tissues, and can cause pain, swelling, stiffness and difficulty moving. The World Health Organization estimates that approximately 528 million people were living with it worldwide in 2019. Age, previous joint injury and excess weight are among its risk factors, but developing osteoarthritis is not an inevitable consequence of getting older. [WHO osteoarthritis fact sheet](https://www.who.int/news-room/fact-sheets/detail/osteoarthritis).

The American Heart Association's Life's Essential 8 framework takes a similarly broad view of cardiovascular health. It includes diet, physical activity, nicotine exposure, sleep, body mass index, blood lipids, blood glucose and blood pressure. These measures combine everyday behaviors with clinical information. A cardiovascular assessment therefore extends beyond a cholesterol result or blood-pressure reading, creating opportunities to discuss several aspects of health during the same appointment. [American Heart Association framework](https://professional.heart.org/en/science-news/lifes-essential-8).

What can people do for their heart and joints now?

Quick answer: Established recommendations support tailored exercise, appropriate weight management and attention to cardiovascular risk factors.

For people with osteoarthritis, NICE recommends exercise adapted to individual needs, including muscle strengthening and aerobic activity. Some discomfort can occur when starting, but regular participation can improve pain, function and quality of life over time. For people also living with overweight or obesity, supported weight loss can provide additional benefits. These recommendations concern managing existing osteoarthritis; they do not promise that lifestyle changes will prevent every future case. [NICE osteoarthritis recommendations](https://www.nice.org.uk/guidance/ng226/chapter/recommendations).

For cardiovascular health, the American Heart Association recommends an overall eating pattern emphasizing vegetables, fruit, whole foods and healthy protein sources, alongside avoiding tobacco and managing blood pressure, cholesterol and blood glucose. Its general activity recommendation for adults includes at least 150 minutes of moderate exercise weekly. For someone with painful joints, working toward activity goals through an adapted plan can connect cardiovascular care with rehabilitation. [Life's Essential 8](https://www.heart.org/en/healthy-living/healthy-lifestyle/lifes-essential-8).

Frequently Asked Questions

No. Risk increases with age, but osteoarthritis is not inevitable. Previous joint injuries and excess weight also contribute to risk. [WHO](https://www.who.int/news-room/fact-sheets/detail/osteoarthritis).

No. Osteoarthritis involves the whole joint and surrounding tissues. It commonly affects the knees, hips, hands and spine. [WHO](https://www.who.int/news-room/fact-sheets/detail/osteoarthritis).

Generally, no. NICE recommends tailored exercise, with supervised sessions considered where helpful. A clinician or physiotherapist can adapt activity to individual needs. [NICE guidance](https://www.nice.org.uk/guidance/ng226/chapter/recommendations).

For people with osteoarthritis who also have overweight or obesity, supported weight loss can reduce pain and improve physical function and quality of life. [NICE guidance](https://www.nice.org.uk/guidance/ng226/chapter/recommendations).

Yes. Sleep is one of the eight components in the American Heart Association's cardiovascular health framework, alongside behavioral measures and clinical risk factors. [American Heart Association](https://professional.heart.org/en/science-news/lifes-essential-8).

References

  1. Luo J, et al. Cardiovascular health and osteoarthritis risk: a prospective cohort study with proteomic insights from UK Biobank. RMD Open. 2026;12:e006881. [Study](https://doi.org/10.1136/rmdopen-2026-006881).
  2. American Heart Association. Life's Essential Eight: Updating and Enhancing the American Heart Association's Cardiovascular Health Construct. June 29, 2022. [Scientific advisory overview](https://professional.heart.org/en/science-news/lifes-essential-8).
  3. World Health Organization. Osteoarthritis. July 14, 2023. [Fact sheet](https://www.who.int/news-room/fact-sheets/detail/osteoarthritis).
  4. National Institute for Health and Care Excellence. Osteoarthritis in over 16s: diagnosis and management. Guideline NG226. 2022. [Recommendations](https://www.nice.org.uk/guidance/ng226/chapter/recommendations).
  5. American Heart Association. Life's Essential 8. [Cardiovascular health recommendations](https://www.heart.org/en/healthy-living/healthy-lifestyle/lifes-essential-8).