Muscles and Tendons: How Your Musculoskeletal System Works

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Our muscles and tendons enable us to move and allow vital organs to function. The muscular system provides structural support to the skeleton, protects internal organs, and generates heat to maintain body temperature. The human body contains three types of muscle tissue: skeletal muscles for voluntary movement, cardiac muscle in the heart, and smooth muscles in internal organs and blood vessels.
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Written and reviewed by iMedic Medical Editorial Team | Specialists in anatomy and physiology

📊 Quick facts about muscles and tendons

Total Skeletal Muscles
600+
in the human body
Body Mass
40%
of total body weight
Muscle Types
3 Types
skeletal, cardiac, smooth
Longest Tendon
Achilles
up to 30 cm
Muscle Cell Length
Up to 30 cm
longest cells in body
MeSH Code
A02.633
Muscles

💡 The most important things you need to know

  • Three muscle types: Skeletal muscles (voluntary), cardiac muscle (heart), and smooth muscles (internal organs) each serve distinct functions
  • Over 600 skeletal muscles: These muscles work together in coordinated groups to enable smooth, controlled movements
  • Tendons connect muscles to bones: Made of strong collagen fibers, tendons transmit force from muscle contractions to move the skeleton
  • Muscles generate body heat: Muscle contractions produce heat that helps maintain normal body temperature
  • No new muscle cells after birth: Muscles grow larger through cell enlargement, not by creating new cells
  • Energy from mitochondria: Muscle cells contain many mitochondria to produce the energy needed for contraction
  • Lactic acid from oxygen debt: When muscles work without sufficient oxygen, lactic acid builds up causing fatigue

What Are the Three Types of Muscles in the Human Body?

The human body contains three distinct types of muscles: skeletal muscles (voluntary muscles that attach to bones and enable movement), cardiac muscles (found only in the heart, involuntary and highly durable), and smooth muscles (found in blood vessel walls, airways, and digestive tract, also involuntary). Each type has unique structural and functional characteristics suited to its specific role.

Understanding the different types of muscle tissue is fundamental to understanding how the human body moves, functions, and maintains vital processes. While all muscle tissue shares the ability to contract and generate force, each type has evolved specialized characteristics that make it perfectly suited for its particular function in the body.

The muscular system is one of the largest organ systems in the human body, comprising approximately 40% of total body weight in adults. This remarkable system not only enables movement but also plays crucial roles in maintaining posture, stabilizing joints, generating heat, and even assisting with essential functions like breathing and digestion. The coordinated action of muscles throughout the body allows for everything from the subtle movements of facial expressions to the powerful force needed for running or lifting heavy objects.

Each muscle type has developed specific adaptations over millions of years of evolution. These adaptations include differences in cell structure, energy metabolism, response to neural signals, and the ability to sustain prolonged activity. Understanding these differences helps explain why certain muscles can work continuously without fatigue while others tire quickly after intense activity.

Cardiac Muscle: The Heart's Tireless Engine

Cardiac muscles are found exclusively in the heart and represent one of the most remarkable tissues in the human body. These muscles are both durable and fast-acting, capable of contracting continuously throughout a person's entire lifetime without conscious control. The heart beats approximately 100,000 times per day, or about 3 billion times over an average lifespan, making cardiac muscle the most enduring muscle tissue in the body.

Unlike skeletal muscles, cardiac muscle cells are branched and interconnected through specialized junctions called intercalated discs. These connections allow electrical signals to pass rapidly between cells, enabling the heart to contract as a synchronized unit. This coordinated contraction is essential for efficiently pumping blood throughout the body. Cardiac muscle cells also contain numerous mitochondria, providing the constant energy supply needed for continuous beating.

Skeletal Muscles: Voluntary Movement

Skeletal muscles are attached to bones through tendons and are responsible for all voluntary movements. These muscles work quickly but fatigue faster than other muscle types because they are designed for short bursts of activity rather than continuous work. Skeletal muscles enable us to move, speak, swallow, chew, and express emotions through facial movements. They also provide stability to the skeleton and protect internal organs from injury.

The nervous system directly controls skeletal muscles through motor neurons. When you decide to move your arm or leg, nerve signals travel from your brain through your spinal cord and peripheral nerves to stimulate specific muscle fibers. This voluntary control distinguishes skeletal muscles from cardiac and smooth muscles, which operate automatically without conscious thought.

Smooth Muscles: Automatic Internal Functions

Smooth muscles are found in the walls of hollow organs and structures throughout the body, including blood vessels, airways, the urinary bladder, and the gastrointestinal tract. Unlike skeletal muscles, smooth muscles cannot be controlled voluntarily. They are highly durable but work slowly, making them ideal for sustained contractions that maintain pressure in blood vessels or move food through the digestive system.

The contractions of smooth muscles play vital roles in many body functions. In blood vessels, smooth muscle tone regulates blood pressure and blood flow to different organs. In the airways, smooth muscles control the diameter of bronchi, affecting how easily air can move in and out of the lungs. In the digestive tract, rhythmic smooth muscle contractions (peristalsis) push food along from the esophagus to the rectum.

Comparing the Three Types of Muscle Tissue
Characteristic Skeletal Muscle Cardiac Muscle Smooth Muscle
Location Attached to bones Heart only Internal organs, blood vessels
Control Voluntary Involuntary Involuntary
Speed Fast contractions Moderate, rhythmic Slow contractions

How Are Skeletal Muscles Structured?

Skeletal muscles are composed of bundled muscle fibers (cells) held together by connective tissue. Each muscle cell contains multiple nuclei because it forms from the fusion of several cells during development. The entire muscle is surrounded by a connective tissue sheath, and nerves within this tissue transmit signals that control muscle contraction.

The structure of skeletal muscle is remarkably organized, reflecting its function as a force-generating machine. At the microscopic level, each skeletal muscle is made up of thousands of individual muscle fibers, which are actually single muscle cells that can be extremely long, sometimes stretching up to 30 centimeters in length. These are among the longest cells in the human body.

Skeletal muscle fibers have a unique characteristic: each fiber contains multiple nuclei. This multinucleated structure occurs because muscle fibers form during development through the fusion of many smaller cells called myoblasts. Having multiple nuclei allows the cell to produce proteins more efficiently across its entire length, which is essential for building and maintaining the contractile machinery within the muscle fiber.

The organization of muscle continues at higher levels. Multiple muscle fibers are bundled together into fascicles, which are visible to the naked eye as the grain of meat when you cut through a piece of muscle. Several fascicles are then bundled together and wrapped in connective tissue to form the complete muscle. This hierarchical organization allows muscles to generate tremendous force while remaining flexible and coordinated.

How Skeletal Muscles Are Controlled by the Nervous System

Skeletal muscle contractions are controlled by our voluntary will through the nervous system. When you decide to move, a nerve signal originates in the motor cortex of your brain and travels through the spinal cord to reach the appropriate motor neuron. The nerve signal then travels along nerve fibers that penetrate into the muscle tissue, ultimately reaching specialized junctions with individual muscle fibers.

At the neuromuscular junction, the nerve releases chemical messengers (neurotransmitters) that trigger electrical changes in the muscle fiber membrane. This electrical signal spreads rapidly along the muscle fiber and deep into the cell through a network of tubules, initiating the molecular events that cause the muscle to contract. The entire process from brain signal to muscle contraction occurs in milliseconds.

Blood Supply: Oxygen and Nutrients for Working Muscles

Muscles receive oxygen and nutrients from blood vessels that penetrate into the muscle tissue. An extensive network of capillaries surrounds each muscle fiber, ensuring that oxygen and fuel molecules can quickly reach the cells that need them. When a muscle works harder, blood flow to that muscle increases dramatically, sometimes up to 20 times the resting level, to meet the increased demand for oxygen and nutrients.

This increased blood flow also helps remove waste products like carbon dioxide and lactic acid that accumulate during exercise. The warming sensation you feel in your muscles during exercise is partly due to this increased blood flow and partly due to the heat generated by muscle contractions.

Energy Production: The Role of Mitochondria

Muscles require enormous amounts of energy when they contract. To meet this demand, muscle cells contain many mitochondria, the cellular powerhouses that produce ATP (adenosine triphosphate), the molecule that directly fuels muscle contraction. The energy for ATP production comes from the nutrients we consume in food, primarily carbohydrates and fats.

During moderate exercise, mitochondria efficiently convert nutrients to ATP using oxygen (aerobic metabolism). This process is highly efficient and can continue for extended periods as long as oxygen supply meets demand. However, during intense exercise when oxygen cannot be delivered fast enough, muscles must rely on anaerobic metabolism, which produces ATP quickly but generates lactic acid as a byproduct.

Lactic Acid: What Happens When Muscles Don't Get Enough Oxygen

When a muscle works intensely and doesn't receive sufficient oxygen, nutrients cannot be completely broken down through normal aerobic pathways. Instead, the muscle relies on anaerobic glycolysis, which produces energy quickly but results in the accumulation of lactic acid. This buildup of lactic acid contributes to the burning sensation and fatigue you feel during strenuous exercise.

Contrary to popular belief, lactic acid is not a waste product that damages muscles. It's actually an important fuel that can be used by other tissues, including the heart, and the liver can convert it back to glucose. The fatigue you feel during intense exercise is more complex than simple lactic acid accumulation and involves multiple factors including depletion of energy stores and neural fatigue.

Muscle Growth: Why We Don't Make New Muscle Cells

After birth, the body does not create new skeletal muscle cells. Instead, when muscles grow larger through exercise or during normal development, existing muscle cells increase in size (hypertrophy). Individual muscle fibers can grow substantially, both in diameter and sometimes in length, to accommodate increased demands. This is why strength training makes muscles larger without creating new cells.

However, the body does maintain a population of satellite cells, which are dormant muscle precursor cells located alongside mature muscle fibers. These cells can be activated in response to muscle damage or intense training, fusing with existing fibers to help repair damage and potentially contribute to muscle growth. Some research suggests these cells may occasionally form new fibers, though this is limited compared to the growth of existing cells.

How Do Tendons Connect Muscles to Bones?

Tendons are tough, fibrous bands of connective tissue that attach muscles to bones. They consist primarily of densely packed collagen fibers, which give them tremendous tensile strength. The shortest tendons are only a few millimeters long, while the longest, the Achilles tendon, can reach approximately 30 centimeters.

Tendons serve as the critical mechanical link between muscles and the skeletal system. When a muscle contracts, the force generated is transmitted through the tendon to move the attached bone. This seemingly simple function requires remarkable engineering: tendons must be strong enough to withstand enormous forces without breaking, yet flexible enough to allow smooth movement around joints.

The structure of tendons reflects these demanding requirements. They are composed primarily of collagen, a protein that forms extremely strong fibers when arranged in parallel bundles. These collagen fibers are aligned along the direction of force transmission, maximizing the tendon's ability to resist pulling forces. The organization is so precise that tendons can withstand forces many times greater than body weight.

Where a muscle ends, its surrounding connective tissue transitions seamlessly into the tendon. This junction is not a simple attachment but a complex interlocking of muscle fibers with tendon tissue that distributes force across a large area, preventing stress concentrations that could cause injury. At the other end, the tendon attaches to bone through another specialized junction where collagen fibers penetrate into the bone surface.

Tendon Sheaths and Bursae: Protection for High-Stress Areas

Connective tissue forms the structural foundation for tendons, making them remarkably strong and somewhat elastic. Because tendons attach so firmly to muscles and bones, they can transmit tremendous forces without detaching. However, in areas where tendons experience high friction or must slide over bony prominences, additional protective structures are necessary.

Some tendons, particularly those in the hands and feet, are surrounded by tendon sheaths, which are tube-like channels made of connective tissue. These sheaths contain lubricating fluid that allows the tendon to glide smoothly with minimal friction. The tendons controlling finger movements, for example, pass through elaborate pulley systems of sheaths that keep them close to the bones while allowing free movement.

Bursae are another protective structure that cushion tendons where they pass over hard surfaces. These fluid-filled sacs function like tiny water balloons, reducing friction and absorbing shock. Both tendon sheaths and bursae are particularly important in areas where tendons are subjected to large forces or repeated movements, helping prevent wear and injury over a lifetime of use.

The Achilles Tendon: The Body's Strongest Tendon

The Achilles tendon, connecting the calf muscles to the heel bone, is the strongest and largest tendon in the human body. It can withstand forces of up to 12 times body weight during running and jumping activities. Despite its strength, the Achilles tendon is also one of the most commonly injured tendons, particularly in athletes who perform repetitive jumping or sudden accelerations.

What Are the Major Muscle Groups in the Body?

The human body contains over 600 skeletal muscles organized into functional groups. Major muscle groups include the head and neck muscles (for facial expressions, chewing, and head movement), shoulder and arm muscles (for lifting and manipulation), trunk muscles (for posture and breathing), and leg muscles (for walking and running).

The muscular system is organized into functional groups that work together to produce coordinated movements. Understanding these major muscle groups helps explain how complex movements are achieved through the coordinated action of multiple muscles. Rarely does a single muscle work in isolation; instead, groups of muscles contract together while others relax to produce smooth, controlled motion.

This coordination involves several types of muscle roles. The primary mover (agonist) is the muscle that produces the main force for a movement. Synergists are muscles that assist the primary mover. Antagonists are muscles that produce the opposite movement and must relax to allow the desired motion. Stabilizers are muscles that hold other body parts steady to provide a stable base for movement.

Head and Face Muscles

The head contains numerous small, superficial muscles that control facial expressions, including opening and closing the eyes and mouth. These muscles enable us to communicate emotions non-verbally, allowing us to wrinkle our foreheads, smile, frown, and form our lips in countless ways. The ability to read facial expressions is fundamental to human social interaction, and these small muscles make such communication possible.

Four powerful chewing muscles (masseters and temporalis, among others) are located around each jaw joint. When these muscles contract together, they close the jaw with tremendous force. The masseter is often cited as the strongest muscle in the body relative to its size, generating bite forces that can exceed 600 newtons. Other muscles control the complex movements of the tongue and throat necessary for speaking and swallowing.

Neck and Shoulder Muscles

The neck contains several important muscles that enable head movement and maintain head position. The sternocleidomastoid muscle, running from the sternum and clavicle to behind the ear, allows you to turn and tilt your head. Deep neck muscles help stabilize the cervical spine and hold the head upright against gravity.

The shoulder region contains multiple muscles that work together to provide both mobility and stability to the shoulder joint. Key muscles include the trapezius, which lifts the arm overhead and holds the shoulder blade in position, the latissimus dorsi on the side of the back that pulls the arm down and rotates it inward, the pectoralis major that brings the arm across the chest, and the deltoid that gives the shoulder its rounded shape and lifts the arm to horizontal position.

The rotator cuff is a group of four small muscles that surround the shoulder joint and are crucial for arm rotation and shoulder stability. These muscles work constantly to keep the ball of the upper arm bone centered in its shallow socket during movement. Rotator cuff injuries are common because these small muscles are easily overwhelmed by the larger muscles they must control.

Arm and Hand Muscles

The upper arm contains two major muscles that perform opposite functions. The biceps muscle on the front of the upper arm runs from the shoulder blade to the forearm near the elbow. It bends the elbow and also rotates the forearm so the palm faces upward. The triceps muscle on the back of the upper arm extends from the shoulder blade to the elbow and straightens the elbow joint.

The forearm contains nineteen different muscles working in coordinated groups to bend and straighten the wrist and fingers, rotate the forearm, and grip objects. Many of these muscles have long tendons that cross the wrist and extend into the hand, allowing the forearm muscles to move the fingers without adding bulk to the hand itself. This arrangement keeps the hand relatively slender while maintaining considerable strength.

The hand contains numerous small muscles responsible for fine motor control. The brain area controlling hand movements is disproportionately large compared to the hand's size, reflecting the importance and complexity of hand function in humans. Specialized muscles in the thumb allow the opposition movement that distinguishes human hands from those of most other animals.

Back Muscles

The back contains many muscles arranged in layers from superficial to deep. Superficial muscles like the trapezius and latissimus dorsi primarily move the shoulders and arms. Deeper muscles run along the length of the spine and work together to extend, rotate, and stabilize the vertebral column.

The deep back muscles are crucial for maintaining posture and protecting the spinal cord. These muscles work constantly, making small adjustments to keep the body balanced and upright. Weakness or imbalance in these muscles is a common contributor to back pain and postural problems.

Chest and Abdominal Muscles

Chest muscles can be divided into superficial and deep layers. The superficial muscles, including the pectoralis major and minor, are primarily involved in arm movements. The deep muscles, particularly the intercostal muscles between the ribs and the diaphragm, are essential for breathing.

The intercostal muscles raise and lower the ribs during breathing, especially during rapid or deep breathing. The diaphragm is a dome-shaped muscle that separates the chest from the abdomen. When it contracts, it flattens and moves downward, expanding the chest cavity and drawing air into the lungs. Relaxation of the diaphragm allows the lungs to recoil and push air out during exhalation.

The abdominal muscles form multiple layers that protect the organs of the abdominal cavity. The rectus abdominis runs vertically on either side of the midline, while the oblique muscles run diagonally, and the transversus abdominis runs horizontally. Together, these muscles support internal organs, assist breathing, and generate the increased abdominal pressure needed for activities like lifting heavy objects, coughing, or urination.

Pelvic and Hip Muscles

The pelvic floor is a muscular platform at the base of the pelvis consisting of multiple muscles that support the pelvic organs and control the openings of the urethra, vagina (in women), and rectum. These muscles prevent urinary and fecal incontinence and play important roles in sexual function and childbirth.

The gluteal muscles form the buttocks and are among the most powerful muscles in the body. The gluteus maximus is the largest muscle in the body and is responsible for extending the hip, as when climbing stairs or rising from a seated position. The gluteus medius, located beneath it, is crucial for stabilizing the pelvis during walking and running.

Thigh and Leg Muscles

The thigh contains several large muscle groups. On the front, the quadriceps is actually a group of four muscles that work together to extend the knee and flex the hip. These muscles are essential for standing up, walking, and climbing. On the back of the thigh, the hamstring muscles (three muscles working together) extend the hip and flex the knee, playing crucial roles in walking, running, and decelerating the leg.

The inner thigh contains adductor muscles that pull the leg toward the body's midline. These muscles are important for lateral stability and are heavily used in activities that require side-to-side movement. The sartorius, the longest muscle in the body, crosses both the hip and knee joints, allowing the position used when sitting cross-legged.

The lower leg contains muscles arranged around the tibia (shin bone) and fibula. The gastrocnemius and soleus on the back of the leg form the calf and connect to the Achilles tendon. These powerful muscles push off during walking and running. Muscles on the front and sides of the lower leg control foot position and toe movement.

Foot Muscles

The foot's primary muscular function is supporting the arches along with strong ligaments. Small muscles on the bottom of the foot can curl and spread the toes, while small muscles on the top help extend the toes. Although small, these muscles contribute to balance and provide fine control during walking on uneven surfaces.

How Do Muscles Contract and Produce Movement?

Muscles contract when nerve signals trigger the release of calcium within muscle fibers, activating specialized proteins (actin and myosin) that slide past each other to shorten the muscle. This sliding filament mechanism requires energy from ATP and occurs simultaneously in millions of sarcomeres (the basic contractile units) along the muscle fiber.

The mechanism of muscle contraction is one of the most elegant examples of biological engineering. At the molecular level, contraction occurs through the interaction of two proteins, actin and myosin, arranged in overlapping filaments within the muscle fiber. When activated, myosin molecules grab onto actin filaments and pull them inward, shortening the entire muscle fiber.

This process requires precise coordination. The muscle fiber is divided into thousands of tiny units called sarcomeres, each containing the necessary protein machinery for contraction. When a nerve signal arrives, calcium is released throughout the fiber simultaneously, activating all sarcomeres at once. The result is a coordinated contraction that can generate significant force while occurring in a fraction of a second.

The energy for contraction comes from ATP molecules, which are constantly regenerated by mitochondria and other metabolic processes. Each contraction cycle requires ATP, and during sustained activity, muscles may go through billions of these cycles. The efficiency of this process determines how long a muscle can work before fatigue sets in.

Did You Know: Muscles Can Only Pull, Never Push

All muscles can only generate force by contracting (pulling). They cannot actively push or extend themselves. This is why muscles are arranged in opposing pairs: when one muscle contracts to move a joint in one direction, the opposing muscle must relax. To move the joint back, the roles are reversed. This arrangement, called antagonistic pairing, is fundamental to how the muscular system produces controlled movement.

What Can Go Wrong with Muscles and Tendons?

Common muscle and tendon problems include strains (overstretched or torn muscle fibers), tendinitis (inflammation of tendons from overuse), muscle cramps, and conditions like fibromyalgia (widespread chronic pain). More serious conditions include muscular dystrophies (genetic diseases causing progressive weakness) and rhabdomyolysis (breakdown of muscle tissue).

The muscular system, despite its remarkable capabilities, is susceptible to various injuries and disorders. Understanding these conditions helps recognize when professional medical attention may be needed and how to prevent common problems through proper care and exercise.

Muscle strains occur when muscle fibers are stretched beyond their capacity or torn. These injuries range from mild (microscopic fiber damage) to severe (complete muscle rupture). Symptoms include pain, swelling, weakness, and sometimes bruising. Most strains heal with rest, ice, compression, and elevation, but severe strains may require medical intervention or even surgery.

Tendinitis develops when tendons become inflamed, usually from repetitive overuse. Common examples include tennis elbow (affecting the outer elbow), golfer's elbow (inner elbow), and Achilles tendinitis. These conditions cause pain, tenderness, and sometimes swelling. Treatment typically involves rest, anti-inflammatory medications, physical therapy, and modification of activities that aggravate the condition.

Chronic conditions affecting muscles include polymyalgia rheumatica (an inflammatory condition causing muscle pain and stiffness, particularly in older adults), fibromyalgia (widespread chronic pain with increased pain sensitivity), and various forms of muscular dystrophy (genetic diseases causing progressive muscle weakness and loss of muscle mass).

Frequently Asked Questions About Muscles and Tendons

Medical References and Sources

This article is based on current medical research and standard anatomy and physiology textbooks. All claims are supported by scientific evidence from peer-reviewed sources.

  1. Standring S, et al. (2021). "Gray's Anatomy: The Anatomical Basis of Clinical Practice." 42nd Edition. Elsevier. Comprehensive anatomical reference for muscles and tendons.
  2. Hall JE, Hall ME (2021). "Guyton and Hall Textbook of Medical Physiology." 14th Edition. Elsevier. Standard reference for muscle physiology and contraction mechanisms.
  3. American College of Sports Medicine (2022). "ACSM's Guidelines for Exercise Testing and Prescription." 11th Edition. Wolters Kluwer. Evidence-based guidelines for muscle function and exercise.
  4. Frontera WR, Ochala J (2015). "Skeletal Muscle: A Brief Review of Structure and Function." Calcified Tissue International. 96(3):183-195. PubMed Peer-reviewed overview of skeletal muscle structure and function.
  5. Wang JH (2006). "Mechanobiology of tendon." Journal of Biomechanics. 39(9):1563-1582. PubMed Comprehensive review of tendon structure and biomechanics.
  6. Mukund K, Bhattacharya S (2019). "Skeletal Muscle: A Review of Molecular Structure and Function." Cells. 8(3):232. PubMed Modern review of muscle molecular biology.

Evidence grading: This article uses the GRADE framework (Grading of Recommendations Assessment, Development and Evaluation) for evidence-based medicine. Content is based on standard medical textbooks and peer-reviewed anatomical and physiological research.

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