Irregular Periods: Causes, Treatment & When to See a Doctor

Medically reviewed | Last reviewed: | Evidence level: 1A
Irregular periods occur when your menstrual cycle varies significantly from the typical 21-35 day pattern, or when periods are missed entirely. Common causes include hormonal imbalances such as PCOS, stress, significant weight changes, perimenopause, and hormonal contraceptives. While some cycle variation is normal, persistent irregularity may require medical evaluation, especially if you're trying to conceive or haven't had a period for more than three months.
📅 Updated:
⏱️ Reading time: 12 minutes
Written and reviewed by iMedic Medical Editorial Team | Specialists in gynecology and reproductive medicine

📊 Quick facts about irregular periods

Normal cycle
21-35 days
typical range
Prevalence
14-25%
of women affected
PCOS affects
6-12%
of reproductive-age women
Seek care if missed
3+ months
without pregnancy
Perimenopause onset
Age 40+
typical start
ICD-10 code
N91/N92
Menstrual disorders

💡 The most important things you need to know

  • Some variation is normal: A cycle between 21-35 days is considered regular, and occasional variations of a few days are common and usually not concerning
  • PCOS is a leading cause: Polycystic ovary syndrome affects 6-12% of women and is one of the most common causes of irregular periods
  • Stress can delay your period: Chronic stress affects hormones that regulate ovulation, which can cause missed or late periods
  • Track your cycles: Recording your periods in a calendar or app helps identify patterns and provides valuable information for healthcare providers
  • Seek care if periods stop for 3+ months: Amenorrhea (absent periods) for more than three months should be evaluated, especially if you're not pregnant
  • Pregnancy is a common cause: Always take a pregnancy test if you've missed a period and there's any possibility of pregnancy

What Are Irregular Periods?

Irregular periods occur when your menstrual cycle length varies significantly from month to month, when periods are missed entirely, or when bleeding patterns are unpredictable. A regular menstrual cycle typically ranges from 21 to 35 days, with bleeding lasting 2 to 7 days.

The menstrual cycle is controlled by a complex interplay of hormones, primarily estrogen and progesterone, which are regulated by signals from the brain's hypothalamus and pituitary gland. When this delicate hormonal balance is disrupted, it can lead to irregular periods. Understanding what constitutes an irregular period is the first step toward identifying whether you need medical attention.

A regular menstrual cycle typically occurs every 21 to 35 days, with most women experiencing a cycle of approximately 28 days. The length of your period (the days you actually bleed) normally ranges from 2 to 7 days. However, it's important to recognize that there is significant natural variation between women, and what's regular for one person may differ from another. The key factor is consistency in your own cycle pattern.

Irregular periods can manifest in several ways. Some women experience cycles that are consistently shorter than 21 days (polymenorrhea) or longer than 35 days (oligomenorrhea). Others may have completely unpredictable cycles that vary dramatically from month to month. Amenorrhea refers to the complete absence of menstruation, either when periods have never started (primary amenorrhea) or when previously regular periods have stopped for three months or more (secondary amenorrhea).

Tracking your menstrual cycle can be extremely helpful in identifying irregularities. You can do this by marking the first day of your period on a calendar or using a period-tracking app on your smartphone. By recording this information over several months, you can establish your typical pattern and more easily notice any changes that might warrant medical attention.

Types of menstrual irregularities:
  • Oligomenorrhea: Infrequent periods occurring more than 35 days apart
  • Polymenorrhea: Frequent periods occurring less than 21 days apart
  • Amenorrhea: Complete absence of menstruation for 3+ months
  • Metrorrhagia: Bleeding between periods or irregular spotting
  • Menorrhagia: Abnormally heavy or prolonged bleeding during periods

What Causes Irregular or Missed Periods?

The most common causes of irregular periods include hormonal contraceptives, polycystic ovary syndrome (PCOS), stress, significant weight changes, thyroid disorders, perimenopause, and pregnancy. Some women naturally have variable cycles without any underlying medical condition.

Understanding the underlying cause of irregular periods is essential for determining the appropriate treatment approach. The menstrual cycle is influenced by numerous factors, and disruptions to any part of the hormonal system can result in irregular bleeding patterns. Here are the most common causes explained in detail.

Hormonal Contraceptives

Hormonal contraceptives work by preventing ovulation through the administration of synthetic hormones. Birth control pills, hormonal IUDs, contraceptive implants, injections, and vaginal rings can all affect your menstrual pattern. Many women experience lighter periods, irregular spotting (called breakthrough bleeding), or complete cessation of periods while using hormonal contraception.

When you first start hormonal contraceptives, it's common to experience irregular bleeding for the first few months as your body adjusts. Similarly, when stopping hormonal contraception, it may take several months for your natural cycle to regulate. This is particularly true for injectable contraceptives like Depo-Provera, which may affect fertility and cycle regularity for up to a year after discontinuation.

Polycystic Ovary Syndrome (PCOS)

PCOS is one of the most common hormonal disorders affecting women of reproductive age, with prevalence estimates ranging from 6% to 12%. This condition is characterized by hormonal imbalances that interfere with normal ovulation, leading to irregular or absent periods. Women with PCOS often have elevated levels of androgens (male hormones like testosterone), which can cause additional symptoms such as acne, excess facial and body hair (hirsutism), and difficulty losing weight.

The underlying mechanism in PCOS involves insulin resistance in many cases, which leads to increased insulin production. High insulin levels stimulate the ovaries to produce more androgens, further disrupting the hormonal balance needed for regular ovulation. PCOS is also associated with multiple small cysts on the ovaries, though not all women with PCOS have visible cysts on ultrasound.

If you have PCOS and your periods are coming less frequently than every three months, treatment with progestin (a form of progesterone) may be recommended. This is because prolonged exposure to estrogen without the balancing effect of progesterone (which is normally released after ovulation) can cause the uterine lining to build up excessively, potentially increasing the risk of endometrial hyperplasia or cancer over time.

Stress and Lifestyle Factors

Chronic stress has a significant impact on hormonal function and can disrupt your menstrual cycle. When you're under prolonged stress, your body produces increased levels of cortisol (the stress hormone), which can interfere with the hypothalamic-pituitary-ovarian axis that regulates menstruation. This can lead to delayed or missed ovulation, resulting in late or skipped periods.

The hypothalamus, a region of the brain that controls many hormonal processes, is particularly sensitive to stress. Under chronic stress, it may reduce production of gonadotropin-releasing hormone (GnRH), which in turn decreases the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. Without adequate levels of these hormones, ovulation may not occur, and your period may be delayed or absent.

Life changes and environmental factors can also affect your cycle. Moving to a new place, starting a new job, changing schools, or experiencing relationship difficulties can all temporarily disrupt your hormonal balance. Travel across time zones, changes in sleep patterns, and alterations in daily routines may also influence your cycle. Typically, periods return to normal once the stressful situation resolves or you adapt to the new circumstances.

Weight Changes and Eating Disorders

Both significant weight loss and weight gain can affect menstruation. Fat tissue plays an important role in hormone production and metabolism, particularly in converting certain hormones to estrogen. When body fat drops below a certain threshold (typically around 17-22% body fat), the body may not produce enough estrogen to support ovulation and menstruation.

Eating disorders such as anorexia nervosa and bulimia frequently cause amenorrhea due to severe caloric restriction and low body weight. Similarly, excessive exercise, common in athletes and those with exercise addiction, can lead to what's called the "female athlete triad" – a combination of energy deficiency, menstrual dysfunction, and decreased bone density. This condition is particularly common in sports emphasizing leanness, such as gymnastics, ballet, running, and figure skating.

On the other end of the spectrum, significant weight gain, particularly when associated with insulin resistance, can also disrupt hormonal balance and lead to irregular periods. Obesity is closely linked with PCOS and can exacerbate the hormonal imbalances that cause irregular ovulation.

Thyroid Disorders

The thyroid gland produces hormones that regulate metabolism throughout the body, and these hormones have important interactions with reproductive hormones. Both hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid) can cause menstrual irregularities.

Hypothyroidism, characterized by insufficient thyroid hormone production, often causes heavy, prolonged periods (menorrhagia) and can also lead to more frequent periods. Hyperthyroidism, on the other hand, typically causes lighter and less frequent periods, and in severe cases, may cause amenorrhea. Thyroid disorders can usually be effectively managed with medication, which often restores normal menstrual function.

Perimenopause and Menopause

Perimenopause is the transitional phase leading up to menopause, typically beginning in your 40s but sometimes starting in the mid-30s. During this time, estrogen and progesterone levels fluctuate unpredictably, leading to irregular periods. Cycles may become shorter or longer, bleeding may be heavier or lighter, and you may occasionally skip periods entirely.

The duration of perimenopause varies widely, lasting anywhere from a few months to over a decade, with an average of about four years. You've reached menopause when you haven't had a period for 12 consecutive months. After menopause, any vaginal bleeding should be evaluated by a healthcare provider, as it may indicate a medical issue requiring attention.

Pregnancy

A missed period is often the first sign of pregnancy. If there's any possibility you could be pregnant and your period is late, it's important to take a pregnancy test as soon as possible. Home pregnancy tests are highly accurate when used correctly and are readily available at pharmacies and supermarkets.

Early pregnancy symptoms that may accompany a missed period include breast tenderness, fatigue, nausea, frequent urination, and food aversions or cravings. However, some women experience few or no symptoms in early pregnancy, making a missed period the primary indicator. If you suspect pregnancy, confirming it early allows you to begin prenatal care and make informed decisions about your health.

Common causes of irregular periods
Cause Pattern Other symptoms Action
PCOS Infrequent periods, often >35 days apart Acne, excess hair growth, weight gain Consult gynecologist
Stress Delayed or missed periods Anxiety, sleep problems, fatigue Stress management, usually resolves
Thyroid disorder Heavy/frequent OR light/infrequent Weight changes, fatigue, temperature sensitivity Blood test for thyroid function
Perimenopause Variable, unpredictable cycles Hot flashes, mood changes, sleep disturbance Track symptoms, consult if concerned
Contraceptives Spotting, lighter or absent periods Usually none concerning Normal side effect, discuss with provider

When Should You See a Doctor About Irregular Periods?

See a doctor if your period has been absent for more than three months (and you're not pregnant), if you're experiencing extremely heavy or painful periods, if you're bleeding between periods or after menopause, or if irregular periods are affecting your ability to conceive.

While occasional menstrual irregularities are common and often resolve on their own, certain situations warrant medical evaluation. Understanding when to seek care can help you address potential health issues early and avoid unnecessary worry about normal variations.

You should contact a healthcare provider if you experience any of the following situations. If your periods have been absent for more than three consecutive months and you know you're not pregnant, this condition (secondary amenorrhea) should be evaluated to determine the underlying cause and ensure appropriate treatment. Additionally, if you've been trying to conceive for several months without success and have irregular cycles, medical evaluation can help identify potential fertility issues. This is particularly important if you're over 35, as fertility naturally declines with age.

Heavy bleeding that soaks through a pad or tampon every hour for several consecutive hours, or periods lasting longer than seven days, should be evaluated. This type of bleeding can lead to anemia and may indicate underlying conditions such as uterine fibroids, polyps, or bleeding disorders. Similarly, if you experience severe menstrual cramps that don't respond to over-the-counter pain medications or that significantly interfere with your daily activities, you should seek medical advice.

Any vaginal bleeding after you've completed menopause (defined as 12 consecutive months without a period) requires prompt medical evaluation. Post-menopausal bleeding can have various causes, some benign and others more serious, so it's important to determine the cause.

If irregular periods are accompanied by other concerning symptoms such as unusual hair growth on your face or body, significant unexplained weight changes, persistent acne, or signs of thyroid dysfunction (such as unexplained fatigue, weight changes, or temperature sensitivity), these should also prompt a medical consultation to investigate potential hormonal imbalances.

🚨 Seek immediate medical attention if you experience:
  • Severe pelvic pain or cramping
  • Very heavy bleeding (soaking more than one pad/tampon per hour)
  • Bleeding during pregnancy
  • Fever with pelvic pain or unusual discharge
  • Signs of severe anemia (extreme fatigue, dizziness, pale skin, shortness of breath)

Find your local emergency number →

How Are Irregular Periods Diagnosed?

Diagnosis typically involves a detailed medical history, physical examination, and may include blood tests to check hormone levels (FSH, LH, estrogen, progesterone, thyroid hormones, prolactin), a pregnancy test, and imaging studies such as pelvic ultrasound to examine the ovaries and uterus.

When you visit a healthcare provider about irregular periods, they will begin by gathering detailed information about your menstrual history. You'll be asked about the length of your cycles, the duration and heaviness of your periods, when you last had a period, and whether you've noticed any patterns to the irregularity. This is why tracking your periods is so valuable – it provides your healthcare provider with objective data to help with diagnosis.

Your provider will also ask about your overall health, including any chronic conditions, medications you're taking (including supplements and herbal remedies), your stress levels, exercise habits, diet, and any recent weight changes. Your reproductive history, including any previous pregnancies, contraceptive use, and sexual activity, will also be discussed.

Physical Examination

A physical examination may include checking your weight, blood pressure, and looking for signs of hormonal imbalances such as excess hair growth, acne, or skin changes. A pelvic examination may be performed to check for any structural abnormalities of the reproductive organs.

Blood Tests

Blood tests are commonly used to measure hormone levels and identify potential causes of irregular periods. Common tests include:

  • Pregnancy test (hCG): To rule out pregnancy as a cause of missed periods
  • Thyroid function tests (TSH, T3, T4): To assess thyroid function
  • Follicle-stimulating hormone (FSH) and luteinizing hormone (LH): To evaluate ovarian function and detect perimenopause
  • Prolactin: Elevated levels can cause irregular periods
  • Testosterone and other androgens: Often elevated in PCOS
  • Estradiol and progesterone: To assess ovarian hormone production
  • Complete blood count: To check for anemia from heavy bleeding

Imaging Studies

A pelvic ultrasound is often performed to examine the ovaries and uterus. This painless imaging test can identify ovarian cysts (including the multiple small cysts characteristic of PCOS), uterine fibroids, polyps, or other structural abnormalities. The ultrasound may be performed transabdominally (through your abdomen) or transvaginally (using a probe inserted into the vagina for clearer images).

In some cases, additional testing may be needed. An endometrial biopsy involves taking a small sample of the uterine lining to check for abnormal cells. A hysteroscopy uses a thin, lighted scope to look inside the uterus. MRI may be used for more detailed imaging of the reproductive organs when needed.

How Are Irregular Periods Treated?

Treatment depends on the underlying cause and may include hormonal contraceptives to regulate cycles, progestin therapy to protect the uterine lining, lifestyle modifications such as stress management and weight optimization, or treatment of underlying conditions like thyroid disorders or PCOS.

The approach to treating irregular periods varies widely depending on the underlying cause, your overall health, your age, and whether you're trying to become pregnant. In many cases, addressing the root cause will restore regular menstrual cycles.

Lifestyle Modifications

For many women, lifestyle changes can significantly improve menstrual regularity. If stress is contributing to irregular periods, stress management techniques such as regular exercise, adequate sleep, meditation, yoga, or counseling may help. If weight changes are involved, achieving and maintaining a healthy weight through balanced nutrition and regular physical activity can restore hormonal balance and regular ovulation.

For women with eating disorders or excessive exercise habits, working with a healthcare team that may include a physician, nutritionist, and mental health professional is essential. Restoring adequate nutrition and reducing excessive exercise can help resume normal menstrual function, though this process may take time.

Hormonal Treatments

Hormonal contraceptives are commonly used to regulate menstrual cycles, even in women who don't need contraception. Combined oral contraceptives (containing both estrogen and progestin) create predictable "withdrawal bleeds" during the placebo week and can reduce period pain and bleeding. Other hormonal options include the hormonal IUD, contraceptive patch, vaginal ring, or implant.

For women who don't want or can't use estrogen-containing contraceptives, progestin-only options are available. Progestin therapy may also be prescribed to women with infrequent periods (such as those with PCOS) to induce periodic shedding of the uterine lining, which helps prevent the buildup that can increase the risk of endometrial problems.

Treatment for Specific Conditions

If irregular periods are caused by thyroid dysfunction, treatment with thyroid medication usually restores normal cycles. For women with PCOS, treatment may include medications to improve insulin sensitivity (such as metformin), anti-androgen medications to reduce symptoms like acne and excess hair growth, or fertility medications if pregnancy is desired.

Elevated prolactin levels can often be treated with medications called dopamine agonists. Structural abnormalities such as fibroids or polyps may require surgical treatment, depending on their size, location, and the symptoms they're causing.

Fertility Treatment

For women with irregular periods who are trying to conceive, treatment focuses on achieving regular ovulation. This may involve medications such as clomiphene citrate or letrozole that stimulate ovulation, or in some cases, injectable fertility medications. Working with a reproductive endocrinologist can help optimize your chances of conception.

When no treatment is needed:

If your irregular periods are due to temporary stress, a recent change in your routine, or environmental factors, they often return to normal on their own without medical treatment. During perimenopause, some irregularity is expected and doesn't necessarily require treatment unless symptoms are bothersome. Talk to your healthcare provider about what's right for your situation.

How Can You Track Your Menstrual Cycle?

Track your cycle by recording the first day of each period, cycle length, flow heaviness, and any symptoms. Use a calendar, notebook, or smartphone app. This information helps you identify patterns and provides valuable data for healthcare providers.

Tracking your menstrual cycle is one of the most valuable things you can do for your reproductive health. It helps you understand your body's patterns, identify irregularities early, and provides essential information for healthcare providers when you seek medical advice.

There are several methods for tracking your cycle. The simplest approach is marking the first day of your period on a calendar each month. For more detailed tracking, you might use a dedicated notebook or journal. Smartphone apps designed for period tracking offer convenient features such as automatic cycle length calculations, symptom tracking, and predictions of future periods.

When tracking your cycle, record the first day of your period (this is considered day 1 of your cycle), the duration of bleeding, the heaviness of flow (light, medium, heavy), any spotting between periods, and associated symptoms such as cramps, mood changes, breast tenderness, or headaches. Over time, this information creates a valuable picture of your menstrual health.

If you're trying to conceive, tracking ovulation signs can be helpful. These include changes in cervical mucus (which becomes clear and stretchy around ovulation), basal body temperature (which rises slightly after ovulation), and ovulation predictor kit results. Some women also experience mild pelvic pain (mittelschmerz) around the time of ovulation.

Can You Prevent Irregular Periods?

While not all causes are preventable, maintaining a healthy weight, managing stress, getting adequate sleep, exercising moderately (avoiding extremes), and eating a balanced diet can all help support regular menstrual cycles and overall reproductive health.

While some causes of irregular periods (such as genetic factors or certain medical conditions) cannot be prevented, there are several lifestyle factors you can influence to support regular menstrual cycles and overall reproductive health.

Maintaining a healthy weight is important for hormonal balance. Both underweight and overweight states can disrupt menstrual regularity, so aim for a BMI within the healthy range through balanced nutrition and regular physical activity. If you're struggling with weight management, working with a healthcare provider or registered dietitian can help you develop a sustainable approach.

Managing stress through healthy coping mechanisms supports the hormonal systems that regulate menstruation. Regular exercise, adequate sleep (typically 7-9 hours for adults), mindfulness practices, and social support can all help manage stress levels. If you're experiencing chronic stress or anxiety, don't hesitate to seek professional support.

Regular moderate exercise supports overall health and hormonal balance, but excessive exercise can disrupt menstrual cycles. If you're training intensively, ensure you're consuming adequate calories to support your activity level. Athletes should be aware of the female athlete triad and its impact on menstrual function and bone health.

A balanced diet rich in whole foods, including adequate protein, healthy fats, fruits, vegetables, and whole grains, provides the nutrients needed for optimal hormonal function. Some research suggests that certain nutrients, including iron, vitamin D, and omega-3 fatty acids, may be particularly important for menstrual health.

Frequently asked questions about irregular periods

Medical References and Sources

This article is based on current medical research and international guidelines. All claims are supported by scientific evidence from peer-reviewed sources.

  1. American College of Obstetricians and Gynecologists (ACOG) (2023). "Practice Bulletin: Abnormal Uterine Bleeding." ACOG Clinical Guidance Clinical guidelines for evaluation and management of abnormal uterine bleeding.
  2. International PCOS Network (2023). "International evidence-based guideline for the assessment and management of polycystic ovary syndrome." Monash University PCOS Guidelines Comprehensive international guidelines for PCOS diagnosis and treatment.
  3. International Federation of Gynecology and Obstetrics (FIGO) (2018). "FIGO Classification System (PALM-COEIN) for causes of abnormal uterine bleeding." Standardized classification system for causes of abnormal uterine bleeding.
  4. World Health Organization (WHO) (2024). "Sexual and reproductive health: Menstrual health." WHO Reproductive Health WHO guidance on menstrual health and hygiene.
  5. The Lancet (2023). "Global, regional, and national prevalence and incidence of polycystic ovary syndrome." Epidemiological data on PCOS prevalence worldwide.
  6. Practice Committee of the American Society for Reproductive Medicine (2022). "Evaluation and treatment of amenorrhea." ASRM Practice Recommendations Evidence-based approach to evaluating and treating amenorrhea.

Evidence grading: This article uses the GRADE framework (Grading of Recommendations Assessment, Development and Evaluation) for evidence-based medicine. Evidence level 1A represents the highest quality of evidence, based on systematic reviews of randomized controlled trials.

⚕️

iMedic Medical Editorial Team

Specialists in gynecology and reproductive medicine

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