Pet Allergy: Symptoms, Causes & Treatment for Cat and Dog Allergies

Medically reviewed | Last reviewed: | Evidence level: 1A
Pet allergy is an allergic reaction to proteins found in an animal's skin cells, saliva, and urine. Cat and dog allergies are the most common, affecting 10-20% of the global population. Symptoms include sneezing, runny nose, itchy eyes, and in some cases, asthma. While there is no cure, treatments including antihistamines, nasal corticosteroids, and allergen immunotherapy can effectively manage symptoms and improve quality of life.
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⏱️ Reading time: 12 minutes
Written and reviewed by iMedic Medical Editorial Team | Specialists in allergy and immunology

📊 Quick facts about pet allergy

Prevalence
10-20%
of population affected
Most common
Cat allergy
2x more common than dog
Immunotherapy
70-90% effective
after 3-5 years treatment
Symptom onset
Minutes to hours
after exposure
ICD-10 code
J30.4
Allergic rhinitis
SNOMED CT
232347008
Animal dander allergy

💡 The most important things you need to know

  • Pet allergens come from proteins, not fur: The main allergens are found in animal saliva, skin cells (dander), and urine - not the hair itself
  • No pet is truly hypoallergenic: All cats and dogs produce allergens regardless of breed, though some may produce less
  • Cat allergy is more common: Approximately twice as many people are allergic to cats as to dogs
  • Allergens persist in the environment: Pet allergens can remain in a home for 4-6 months after the animal is removed
  • Allergen immunotherapy is highly effective: 3-5 years of treatment can provide 70-90% symptom reduction and lasting benefits
  • Early exposure may be protective: Some research suggests early childhood exposure to pets may reduce allergy risk

What Is Pet Allergy and What Causes It?

Pet allergy is an immune system reaction to proteins (allergens) found in animal skin cells, saliva, and urine. When a person with pet allergy inhales or touches these allergens, their immune system produces antibodies that trigger allergic symptoms. The main cat allergen is called Fel d 1, and the main dog allergen is Can f 1.

Pet allergy develops when the immune system mistakenly identifies harmless proteins from animals as dangerous invaders. This immune response involves the production of immunoglobulin E (IgE) antibodies that recognize and bind to specific pet allergens. When you are exposed to these allergens again, the antibodies signal your immune system to release chemicals like histamine, causing the characteristic symptoms of allergic reactions.

The proteins that cause pet allergies are not actually found in animal fur, as many people believe. Instead, they are produced by oil glands in the skin and are present in the animal's saliva, urine, and dander (tiny flakes of skin). When animals groom themselves, saliva containing allergens is deposited on their fur. As the saliva dries, these allergenic proteins become airborne and can be inhaled by anyone nearby.

Pet allergens are remarkably persistent and can remain in the environment for months after an animal has been removed from a home. These microscopic particles are lighter than pollen and can stay suspended in the air for extended periods. They also attach easily to furniture, carpets, clothing, and other surfaces, making complete avoidance challenging even in homes that have never had pets.

Why Cat Allergy Is More Common

Cat allergy affects approximately twice as many people as dog allergy, and cat allergies also tend to be more severe. This is primarily because of the properties of the main cat allergen, Fel d 1. This protein is extremely small (about 1/10th the size of dust mite allergens), allowing it to remain airborne for hours and penetrate deep into the respiratory system. Fel d 1 is also very sticky and resistant to degradation, meaning it persists in the environment much longer than dog allergens.

Additionally, Fel d 1 is produced by all cats regardless of breed, sex, or coat length. While some individual cats produce less of this allergen than others, no cat breed is truly hypoallergenic. Male cats, particularly unneutered males, tend to produce more Fel d 1 than females, but even female cats produce enough allergen to trigger symptoms in sensitive individuals.

Other Animals That Cause Allergies

While cats and dogs are the most common sources of pet allergies, other furry animals can also trigger allergic reactions. Rabbits, guinea pigs, hamsters, mice, rats, and horses all produce allergens that can cause symptoms in sensitized individuals. Bird allergies, while less common, can also occur and are typically caused by proteins found in bird feathers, droppings, and dander.

Interestingly, some people who are allergic to one type of animal may also react to others due to cross-reactivity between similar proteins. For example, someone allergic to cats may experience symptoms around lions or tigers at a zoo. Understanding which specific animals trigger your symptoms is important for effective management.

Did you know?

Pet allergens are found everywhere - not just in homes with pets. Studies have found measurable levels of cat and dog allergens in schools, offices, public transportation, and even in homes that have never housed pets. These allergens are carried on clothing from pet owners to virtually every environment.

What Are the Symptoms of Pet Allergy?

Pet allergy symptoms typically include sneezing, runny or stuffy nose, itchy and watery eyes, coughing, and skin reactions like hives or eczema. Symptoms usually appear within minutes to hours of exposure and can range from mild to severe. In people with asthma, pet allergens can trigger wheezing, chest tightness, and difficulty breathing.

The symptoms of pet allergy can affect multiple organ systems and vary significantly in severity from person to person. Most people experience respiratory symptoms similar to hay fever, but skin reactions and eye symptoms are also very common. The intensity of symptoms often depends on the level of allergen exposure and individual sensitivity.

Respiratory symptoms are usually the most prominent and include repeated sneezing, especially in rapid succession, along with nasal congestion that can make breathing through the nose difficult. Many people also experience a clear, watery runny nose and post-nasal drip, which can lead to throat irritation and coughing. These symptoms occur because allergens inhaled through the nose trigger inflammation of the nasal passages.

Eye symptoms, known as allergic conjunctivitis, are extremely common with pet allergies. The eyes may become red, itchy, and watery, with a feeling of grittiness or discomfort. Swelling of the eyelids can occur, and dark circles under the eyes (sometimes called "allergic shiners") may develop from chronic congestion affecting blood flow to the area.

Skin Symptoms and Reactions

Contact with pet allergens can cause skin reactions in many allergic individuals. Hives (urticaria) may appear as raised, itchy red welts on areas that have touched the animal. Some people develop eczema or atopic dermatitis, characterized by dry, itchy, inflamed patches of skin. Direct contact with animal saliva, such as from licking, can cause immediate redness and itching at the site of contact.

These skin reactions occur because pet allergens can penetrate the skin barrier and trigger local immune responses. People with existing eczema may find that their condition worsens with pet exposure, even without direct contact, as airborne allergens can settle on the skin and cause inflammation.

Asthma and Severe Reactions

For people with asthma, pet allergies can be particularly problematic. Exposure to pet allergens can trigger asthma attacks, causing wheezing, shortness of breath, chest tightness, and coughing. Research shows that cat and dog allergens are among the most significant triggers for allergic asthma, and approximately 20-30% of people with asthma are sensitized to pet allergens.

Uncontrolled pet allergen exposure in sensitized individuals can lead to worsening asthma over time and increased need for asthma medications. Some studies suggest that early childhood exposure to pets in children who are already sensitized may increase the risk of developing persistent asthma.

Pet allergy symptoms organized by affected body system
Body System Common Symptoms Onset Time Duration
Nose (Rhinitis) Sneezing, runny nose, congestion, itching Minutes to 1 hour Hours to days
Eyes (Conjunctivitis) Itching, redness, watering, swelling Minutes to 1 hour Hours to days
Lungs (Asthma) Wheezing, coughing, shortness of breath, chest tightness Minutes to hours Hours to days
Skin Hives, itching, eczema flare, redness Minutes to hours Hours to weeks
🚨 When to seek emergency care

While rare, severe allergic reactions (anaphylaxis) to pets can occur. Seek emergency medical care immediately if you experience difficulty breathing, swelling of the throat or tongue, rapid heartbeat, dizziness, or loss of consciousness after pet exposure. Find your emergency number →

How Is Pet Allergy Diagnosed?

Pet allergy is diagnosed through a combination of medical history, physical examination, and allergy testing. Skin prick tests apply small amounts of pet allergen extracts to the skin to check for reactions. Blood tests measure specific IgE antibodies against pet allergens. Accurate diagnosis is essential for effective treatment planning.

The diagnostic process for pet allergy begins with a thorough medical history. Your healthcare provider will ask detailed questions about your symptoms, when they occur, what seems to trigger them, and whether you have exposure to pets at home, work, or in other environments. They will also inquire about your family history of allergies and whether you have other allergic conditions like asthma, eczema, or food allergies.

A physical examination typically follows, with particular attention to the nasal passages, eyes, skin, and lungs. Your doctor may look for signs of allergic rhinitis such as pale, swollen nasal tissues, or examine your eyes for signs of allergic conjunctivitis. If asthma is suspected, lung function testing may be performed.

Allergy testing is usually necessary to confirm the diagnosis and identify which specific allergens are causing your symptoms. This is particularly important because many people assume they are allergic to pets when their symptoms may actually be caused by dust mites, mold, or other allergens that happen to be present in homes with pets.

Skin Prick Testing

Skin prick testing (also called puncture or scratch testing) is the most common method for diagnosing pet allergies. During this test, small drops of allergen extracts from cats, dogs, or other animals are placed on your skin, usually on the forearm or back. The skin is then gently pricked through each drop so that a tiny amount of allergen enters the outer layer of skin.

If you are allergic, a raised, red, itchy bump (wheal) will develop at the test site within about 15-20 minutes. The size of the wheal indicates the degree of sensitivity, though it does not necessarily predict the severity of symptoms you will experience in real-life exposure. Skin prick tests are quick, relatively inexpensive, and provide immediate results.

Blood Tests for Pet Allergy

Blood tests (specific IgE tests) measure the levels of antibodies in your blood that react to pet allergens. These tests can be useful when skin testing is not possible, such as in people with severe eczema, those taking certain medications, or when there is a risk of severe allergic reactions. Common blood tests include ImmunoCAP and various specific IgE panels.

While blood tests may be more convenient and have no risk of allergic reactions during testing, they are generally more expensive and results take longer (usually several days). The results are reported in numerical values, with higher numbers indicating greater sensitization.

Component-resolved diagnostics

Advanced testing called component-resolved diagnostics can identify exactly which specific proteins within cat or dog allergens you are sensitized to. This can help predict the severity of your allergy and whether allergen immunotherapy is likely to be effective for you.

How Is Pet Allergy Treated?

Pet allergy treatment includes avoidance measures, medications, and allergen immunotherapy. Antihistamines relieve sneezing and itching, nasal corticosteroid sprays reduce inflammation, and decongestants help with congestion. For long-term relief, allergen immunotherapy (allergy shots or sublingual tablets) can significantly reduce symptoms in 70-90% of patients over 3-5 years of treatment.

The treatment of pet allergy follows a stepwise approach, starting with allergen avoidance and symptomatic medications, and progressing to allergen immunotherapy for those who need more comprehensive management. The best approach depends on the severity of your symptoms, your exposure level, and your individual circumstances and preferences.

Avoidance of pet allergens is the foundation of treatment, but complete avoidance is often impractical, especially for people who own beloved pets or who are exposed to allergens in public environments. Even with the best avoidance measures, most people with pet allergies will need medications to control their symptoms.

Medications for pet allergy work by blocking or reducing the effects of the immune response to allergens. These medications can be used as needed for intermittent exposure or regularly for ongoing symptom control. Many effective allergy medications are available over-the-counter, while others require a prescription.

Antihistamines

Antihistamines are usually the first-line treatment for pet allergy symptoms. These medications block histamine, one of the main chemicals released during allergic reactions. Second-generation (non-sedating) antihistamines like cetirizine (Zyrtec), loratadine (Claritin), and fexofenadine (Allegra) are preferred because they are effective and cause less drowsiness than older antihistamines.

Antihistamines are particularly effective for relieving sneezing, itching, runny nose, and eye symptoms. They work best when taken before exposure to allergens, so if you know you will be visiting a home with pets, taking an antihistamine beforehand can help prevent or reduce symptoms. Antihistamine eye drops can provide additional relief for itchy, watery eyes.

Nasal Corticosteroid Sprays

Nasal corticosteroid sprays are considered the most effective treatment for allergic rhinitis, including pet allergy-related nasal symptoms. These medications reduce inflammation in the nasal passages, relieving congestion, sneezing, itching, and runny nose. Common options include fluticasone (Flonase), mometasone (Nasonex), and budesonide (Rhinocort).

For best results, nasal corticosteroids should be used regularly, as they take several days to reach maximum effectiveness. Proper technique is important - the spray should be directed away from the nasal septum and you should not sniff forcefully after spraying. These medications have an excellent safety profile for long-term use.

Other Medications

Decongestants (such as pseudoephedrine or oxymetazoline nasal spray) can provide short-term relief from nasal congestion. However, nasal decongestant sprays should not be used for more than 3-5 days to avoid rebound congestion. Leukotriene receptor antagonists (like montelukast) may be helpful for some patients, particularly those who also have asthma.

For skin symptoms, topical corticosteroid creams can help manage eczema flares or contact reactions. People with asthma triggered by pet allergens should ensure their asthma is well-controlled with appropriate inhaler medications.

What Is Allergen Immunotherapy for Pet Allergy?

Allergen immunotherapy gradually desensitizes the immune system to pet allergens through regular exposure to increasing amounts of allergen extract. Treatment typically takes 3-5 years and can provide 70-90% symptom reduction with benefits lasting years after treatment ends. It is the only treatment that modifies the underlying allergic disease rather than just treating symptoms.

Allergen immunotherapy, also known as desensitization or allergy vaccination, is the closest thing to a cure for pet allergies. Unlike medications that only control symptoms, immunotherapy actually changes how your immune system responds to allergens, providing long-term relief that can persist even after treatment is stopped.

The therapy works by gradually exposing your immune system to increasing amounts of the allergens you are sensitive to. Over time, this exposure leads to the development of blocking antibodies and regulatory immune cells that prevent the allergic response. The process essentially "re-educates" your immune system to tolerate pet allergens rather than overreacting to them.

Immunotherapy is typically recommended for people with moderate to severe pet allergies that are not adequately controlled with avoidance measures and medications, or for those who wish to reduce their long-term reliance on allergy medications. It is particularly valuable for people who cannot avoid pet exposure, such as veterinarians, pet owners unwilling to part with their animals, or those frequently exposed to pets through family or friends.

Subcutaneous Immunotherapy (Allergy Shots)

Traditional subcutaneous immunotherapy involves regular injections of pet allergen extracts, typically administered at an allergist's office. Treatment begins with a build-up phase lasting several months, during which injections are given one to two times per week with gradually increasing doses. Once the maintenance dose is reached, injections are typically given every 2-4 weeks.

The full course of treatment usually lasts 3-5 years. Studies show that approximately 70-90% of patients experience significant improvement in symptoms, and benefits often continue for years after treatment is completed. Some patients experience such dramatic improvement that they can tolerate living with pets without symptoms.

Sublingual Immunotherapy (Allergy Tablets)

Sublingual immunotherapy involves placing allergen tablets or drops under the tongue daily at home. While sublingual tablets for grass and ragweed pollen are widely available, standardized sublingual products specifically for pet allergies are still being developed and may not be available in all regions. However, some allergists offer sublingual drops prepared from allergen extracts.

The advantages of sublingual therapy include convenience (no need for frequent office visits) and a lower risk of severe allergic reactions compared to injections. However, daily compliance is essential for effectiveness, and the treatment requires taking medication every day for several years.

Is immunotherapy right for you?

Allergen immunotherapy requires a significant time commitment and works best when patients complete the full course of treatment. Discuss with an allergist whether immunotherapy is appropriate for your situation, considering factors like symptom severity, treatment goals, and practical considerations like time and cost.

How Can I Reduce Pet Allergen Exposure?

Reduce pet allergen exposure by creating pet-free zones (especially bedrooms), using HEPA air purifiers and vacuum cleaners, washing bedding weekly in hot water, bathing pets regularly, and keeping surfaces clean. Even with these measures, complete allergen elimination is difficult since pet allergens are sticky, lightweight, and present virtually everywhere.

While complete avoidance of pet allergens is nearly impossible in modern society, implementing environmental control measures can significantly reduce allergen levels and help manage symptoms. These strategies are most effective when combined with medical treatment and should be tailored to your specific situation and the severity of your allergy.

The goal of environmental control is not to achieve zero allergen exposure, which is unrealistic, but to reduce allergen levels below the threshold that triggers your symptoms. This threshold varies from person to person, so you may need to experiment with different combinations of measures to find what works best for you.

Creating Pet-Free Zones

The single most effective measure for reducing allergen exposure is keeping pets out of certain areas of your home, particularly the bedroom. Since you spend about one-third of your life in bed, making the bedroom a pet-free zone can significantly reduce your overall allergen exposure. Keep the bedroom door closed at all times and never allow pets on beds or bedroom furniture.

If possible, limit pets to certain areas of the home with hard flooring rather than carpet, as hard surfaces are easier to clean and harbor fewer allergens. Consider using baby gates or closed doors to create allergen-reduced zones where you can retreat when symptoms flare.

Air Filtration and Cleaning

High-efficiency particulate air (HEPA) purifiers can capture pet allergens and improve air quality. Place HEPA purifiers in rooms where you spend the most time, especially bedrooms and living areas. For maximum effectiveness, choose units rated for the size of your room and run them continuously.

When vacuuming, use a vacuum cleaner with a HEPA filter to prevent allergens from being blown back into the air. Vacuum carpets, rugs, and upholstered furniture at least twice weekly. Consider replacing wall-to-wall carpet with hard flooring if allergies are severe, as carpet acts as a reservoir for allergens.

Wash bedding, including sheets, pillowcases, and blankets, in hot water (at least 60 degrees C / 140 degrees F) weekly to kill dust mites and remove allergens. Use allergen-proof covers on mattresses and pillows to create a barrier between you and accumulated allergens.

Pet Care and Grooming

Regular bathing of pets can temporarily reduce the amount of allergen they shed, though the effect is short-lived (allergen levels return within days). Have someone without allergies bathe the pet weekly using a gentle pet shampoo. Brushing pets outdoors can also help reduce the amount of loose fur and dander in the home.

Always wash your hands thoroughly with soap and water after touching pets, and avoid touching your face, especially your eyes and nose, after pet contact. Change and wash clothing that has been in contact with pets before entering allergen-free zones like the bedroom.

Can I Live With Pets If I Have Pet Allergy?

Many people with pet allergies successfully live with pets by combining multiple strategies: taking daily allergy medications, implementing strict environmental controls, keeping pets out of bedrooms, using air purifiers, and potentially undergoing allergen immunotherapy. The decision should balance quality of life, symptom severity, and available treatment options.

The question of whether to keep or get a pet when you have pet allergies is deeply personal and depends on many factors, including the severity of your allergy, your emotional attachment to animals, the effectiveness of available treatments for you, and your willingness to implement environmental controls.

For many people, the bond with their pet is strong enough that they choose to manage their allergies rather than give up their animal companion. With proper treatment and environmental control, many allergic individuals can live comfortably with pets. However, this requires ongoing effort and may involve some degree of persistent symptoms.

If you are considering getting a pet despite having allergies, spend time with that specific animal before bringing it home. Individual animals produce different amounts of allergens, and you may tolerate some animals better than others. Remember that allergies can worsen with continued exposure, so what seems manageable initially may become more difficult over time.

The Myth of Hypoallergenic Pets

Despite popular belief, truly hypoallergenic cats and dogs do not exist. All cats produce Fel d 1 and all dogs produce Can f 1, regardless of breed, coat type, or shedding characteristics. While some breeds may produce lower levels of allergens or shed less (resulting in less allergen dispersal), no breed is guaranteed to be safe for allergic individuals.

Studies comparing allergen levels in homes with different dog breeds have found no consistent differences between breeds labeled as hypoallergenic and other breeds. Similarly, there is no evidence that certain cat breeds produce less Fel d 1. Individual variation within breeds is much greater than variation between breeds.

If you are determined to get a pet, consider alternatives to cats and dogs. Fish, reptiles, and amphibians do not produce mammalian allergens. However, be aware that some people develop allergies to the food used for fish or to proteins in reptile skin.

Frequently asked questions about pet allergy

Medical References and Sources

This article is based on current medical research and international guidelines. All claims are supported by scientific evidence from peer-reviewed sources.

  1. European Academy of Allergy and Clinical Immunology (EAACI) (2024). "Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis." Allergy Journal European guidelines for allergen immunotherapy in allergic rhinitis. Evidence level: 1A
  2. World Allergy Organization (2023). "WAO White Book on Allergy: Update 2023." World Allergy Organization Comprehensive overview of global allergy burden and management.
  3. Cochrane Database of Systematic Reviews (2023). "Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis." Cochrane Library Systematic review of immunotherapy effectiveness. Evidence level: 1A
  4. ARIA Working Group (2023). "Allergic Rhinitis and its Impact on Asthma Guidelines: 2023 Update." Journal of Allergy and Clinical Immunology International guidelines for allergic rhinitis management.
  5. American Academy of Allergy, Asthma & Immunology (2023). "Pet Allergy: Practice Parameters." Clinical practice guidelines for pet allergy diagnosis and treatment.
  6. Custovic A, et al. (2022). "The effect of indoor allergen exposure on the development and severity of allergic diseases." Journal of Allergy and Clinical Immunology. Research on allergen exposure and disease development.

Evidence grading: This article uses the GRADE framework (Grading of Recommendations Assessment, Development and Evaluation) for evidence-based medicine. Evidence level 1A represents the highest quality of evidence, based on systematic reviews of randomized controlled trials.

⚕️

iMedic Medical Editorial Team

Specialists in allergy, immunology and respiratory medicine

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