Pregnancy Week 5: Symptoms, Baby Development & What to Expect

Medically reviewed | Last reviewed: | Evidence level: 1A
At 5 weeks pregnant (4 weeks + 0 days to 4 weeks + 6 days after your last period), the embryo is approximately 1 millimeter long and consists of three distinct cell layers that will develop into all of your baby's organs, tissues, and body systems. This is around the time you may notice a missed period and begin experiencing early pregnancy symptoms like morning sickness. Week 5 marks the beginning of a critical developmental period that continues through week 10.
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Written and reviewed by iMedic Medical Editorial Team | Specialists in obstetrics and gynecology

📊 Quick facts about pregnancy week 5

Embryo Size
1 mm
About a sesame seed
Gestational Age
Week 5
4+0 to 4+6 days
Trimester
First
Weeks 1-12
Cell Layers
3 layers
Form all organs
Pregnancy Test
Accurate
Can confirm now
ICD-10 Code
Z33.1
Pregnancy state

💡 The most important things to know about week 5

  • The embryo is about 1 millimeter: Approximately the size of a sesame seed, now consisting of three cell layers that will form all body systems
  • Three cell layers are developing: The ectoderm (brain, nervous system, skin), mesoderm (bones, muscles, heart), and endoderm (stomach, intestines, liver)
  • This is when to take a pregnancy test: Week 5 is around when your period would normally arrive, making home pregnancy tests accurate
  • Morning sickness often begins now: Nausea and vomiting are common due to rising hormone levels, affecting up to 80% of pregnant women
  • Critical developmental period: Weeks 5-10 are when all major organs form, making this a sensitive time for embryonic development
  • Contact a healthcare provider: Schedule your first prenatal appointment as soon as you have a positive pregnancy test

What Happens at 5 Weeks Pregnant?

At 5 weeks pregnant, the embryo is approximately 1 millimeter long and consists of three distinct cell layers called the ectoderm, mesoderm, and endoderm. These three layers contain all the cells needed to develop into every organ and tissue in your baby's body. This marks the beginning of organogenesis, the critical period of organ formation that continues through week 10.

Week 5 of pregnancy is calculated as 4 complete weeks plus 0 to 6 days since the first day of your last menstrual period. This may seem confusing since conception typically occurs around week 2, but pregnancy dating conventionally starts from your last period because it provides a consistent reference point. At this stage, the embryo that will develop into your baby is undergoing rapid and remarkable changes at the cellular level.

The embryo now consists of three primary germ layers, each destined to become specific body structures. This three-layer structure is fundamental to all vertebrate development and represents a critical milestone in embryogenesis. The process of forming these three layers, called gastrulation, typically occurs during weeks 3-4, meaning by week 5, this essential groundwork is complete.

Understanding what happens during this week can help you appreciate both the complexity and the vulnerability of early embryonic development. While the embryo is still microscopic, the cellular organization and differentiation occurring now will influence your baby's development for the remainder of the pregnancy.

The Three Cell Layers Explained

Each of the three cell layers has a specific destiny in terms of what organs and tissues it will ultimately form. This differentiation is controlled by complex genetic signaling pathways that ensure each cell type develops in the right place at the right time.

The ectoderm is the outermost layer and will develop into the brain, spinal cord, peripheral nerves, and the entire nervous system. It also forms the skin, hair, nails, tooth enamel, and the lining of the mouth and nose. The neural tube, which is the precursor to the brain and spinal cord, begins forming around this time, which is why adequate folic acid intake is so critical during early pregnancy.

The mesoderm is the middle layer and is responsible for developing the musculoskeletal system including all bones, muscles, cartilage, and connective tissue. It also forms the cardiovascular system including the heart and blood vessels, the kidneys and reproductive organs, and the dermis layer of the skin. The primitive heart begins to form during weeks 5-6, and the first heartbeat often becomes detectable around week 6.

The endoderm is the innermost layer and will become the digestive system including the stomach, intestines, liver, and pancreas. It also forms the respiratory system including the lungs and airways, the thyroid gland, bladder, and the lining of the urinary tract. These internal organ systems are essential for survival outside the womb and undergo extensive development throughout pregnancy.

How Big Is the Baby at 5 Weeks?

At 5 weeks pregnant, the embryo measures approximately 1 millimeter in length, roughly the size of a sesame seed or the tip of a pen. Despite this tiny size, the embryo contains all the cells needed to develop into a complete human being, with the three cell layers now in place to form every organ system.

It can be difficult to conceptualize just how small the embryo is at this stage. One millimeter is about the thickness of a credit card or the diameter of a small pin head. Yet within this minuscule structure, incredibly complex cellular processes are occurring every second, laying the foundation for human development.

The embryo at this stage doesn't look like a baby yet. It has a somewhat elongated shape, often described as resembling a tadpole, with a distinct head end and tail end beginning to differentiate. The amniotic sac that surrounds and protects the embryo is also developing, filled with amniotic fluid that will cushion your baby throughout pregnancy.

Despite its small size, the embryo is now firmly implanted in the uterine wall and has established blood supply connections with your body. The placenta is beginning to form and will eventually take over the role of providing oxygen and nutrients to your developing baby while removing waste products.

What's Developing This Week

Several key developmental processes are occurring during week 5. The neural tube is beginning to form from the ectoderm layer, eventually becoming the brain and spinal cord. The primitive cardiovascular system is also developing, with blood vessels forming and the foundations of the heart being laid down.

The yolk sac, which provided nutrients during the earliest days of development, is still present and continues to support the embryo until the placenta is fully functional. This transition typically occurs around weeks 10-12, after which the placenta becomes the primary source of nutrients and oxygen.

What Symptoms Are Normal at 5 Weeks Pregnant?

Common symptoms at 5 weeks pregnant include a missed period, morning sickness (nausea with or without vomiting), breast tenderness and swelling, fatigue, frequent urination, and mood changes. Many women also experience light spotting, heightened sense of smell, and food aversions. Not all women experience symptoms this early, and the absence of symptoms does not indicate a problem.

Week 5 is often when pregnancy symptoms first become noticeable, primarily because this is around the time your period would normally be due. The hormonal changes occurring in your body, particularly the rising levels of human chorionic gonadotropin (hCG) and progesterone, trigger many of these early pregnancy symptoms.

It's important to understand that pregnancy symptoms vary greatly from woman to woman and even from pregnancy to pregnancy in the same woman. Some women experience multiple intense symptoms early on, while others notice very little change. Both situations are completely normal and do not indicate anything about the health of the pregnancy.

The symptoms you experience are primarily caused by the dramatic hormonal shifts your body is undergoing to support the pregnancy. Your body is working hard to create the optimal environment for embryonic development, which involves significant changes to your cardiovascular, digestive, and immune systems.

Missed Period

A missed period is often the first sign that prompts women to suspect pregnancy. At 5 weeks, you are about one week past when your period would normally arrive (assuming a typical 28-day cycle). However, cycle length varies significantly between women, so some may not notice a missed period until later.

It's worth noting that some women experience light bleeding or spotting around the time their period would be due. This can be confusing, but implantation bleeding is typically lighter and shorter than a normal period. Any bleeding during pregnancy should be mentioned to your healthcare provider, though light spotting is often normal.

Morning Sickness

Despite its name, morning sickness can occur at any time of day or night. Up to 80% of pregnant women experience some degree of nausea during pregnancy, with symptoms typically beginning around weeks 4-6 and peaking around weeks 8-12. For most women, symptoms improve significantly by the second trimester.

The exact cause of morning sickness isn't fully understood, but it's thought to be related to the rapid rise in hCG hormone during early pregnancy. Some researchers believe it may serve a protective function, helping pregnant women avoid potentially harmful foods during the critical period of organ development.

If you're experiencing morning sickness, there are several strategies that may help: eating small, frequent meals; avoiding strong odors; staying hydrated; eating before getting out of bed; and trying ginger or vitamin B6 supplements. Severe nausea and vomiting that prevents you from keeping food or fluids down should be evaluated by a healthcare provider.

Other Common Symptoms

Breast changes: Your breasts may feel tender, swollen, or heavier than usual. The areolas (the area around the nipples) may darken. These changes are caused by hormones preparing your body for breastfeeding and typically continue throughout pregnancy.

Fatigue: Many women experience significant fatigue during the first trimester. Your body is working incredibly hard to support the pregnancy, and rising progesterone levels can make you feel drowsy. Listen to your body and rest when you need to.

Frequent urination: Hormonal changes and increased blood flow to the pelvic area can lead to more frequent trips to the bathroom. This symptom often improves in the second trimester before returning in the third trimester as the growing uterus puts pressure on the bladder.

Mood changes: Hormonal fluctuations can affect your emotions, causing mood swings, irritability, or heightened emotional sensitivity. This is normal but can be challenging. Seek support from loved ones and don't hesitate to talk to your healthcare provider if you're struggling.

Common symptoms at 5 weeks pregnant and their causes
Symptom Cause What Helps
Missed period Pregnancy hormones prevent menstruation Take a pregnancy test
Morning sickness Rising hCG and estrogen levels Small meals, ginger, avoid triggers
Breast tenderness Hormonal changes preparing for breastfeeding Supportive bra, avoid underwires
Fatigue Rising progesterone, increased metabolism Rest when possible, stay hydrated
Frequent urination Increased blood flow, hormonal changes Don't limit fluids, empty bladder completely

Can I Take a Pregnancy Test at 5 Weeks?

Yes, week 5 is an ideal time to take a home pregnancy test. Most tests are accurate from the first day of your missed period, which typically falls during week 5. Home pregnancy tests detect the hormone hCG (human chorionic gonadotropin) in your urine. For the most accurate results, test with your first morning urine when hCG concentration is highest.

Home pregnancy tests have become remarkably accurate and can detect pregnancy very early. The tests work by detecting hCG, a hormone produced by the cells that will become the placenta. hCG levels rise rapidly after implantation, approximately doubling every 48-72 hours in early pregnancy.

By week 5, hCG levels are typically high enough to be detected by most home pregnancy tests. Some sensitive tests claim to detect pregnancy even before your missed period, though accuracy increases significantly when tested after your period is due. If you test early and get a negative result but your period doesn't arrive, test again in a few days.

A positive home pregnancy test result is very reliable, as false positives are rare. However, a negative result doesn't always mean you're not pregnant, especially if you tested early or if your urine was diluted. If you suspect pregnancy despite a negative test, wait a few days and test again with first morning urine.

How to Take a Pregnancy Test

For the most accurate results, follow these guidelines when taking a home pregnancy test:

  • Test in the morning: Your first morning urine contains the highest concentration of hCG
  • Read the instructions: Different brands may have slightly different procedures
  • Time it correctly: Read results within the time window specified (usually 3-5 minutes)
  • Any second line is positive: Even a faint line indicates pregnancy
  • Don't read results too late: Lines appearing after the time window may be evaporation lines

After a positive home pregnancy test, contact a healthcare provider to schedule your first prenatal appointment. They can confirm the pregnancy with a blood test or ultrasound and begin your prenatal care.

Is Bleeding at 5 Weeks Pregnant Normal?

Light spotting or bleeding can occur around week 5 and is often normal, sometimes coinciding with when your period would normally arrive. However, heavy bleeding, bright red blood, or bleeding accompanied by severe cramping should be evaluated by a healthcare provider promptly, as these could indicate complications such as miscarriage or ectopic pregnancy.

Spotting in early pregnancy is surprisingly common, occurring in up to 25% of pregnancies. In many cases, it's completely benign and doesn't indicate any problem with the pregnancy. The most common cause is implantation bleeding, which occurs when the embryo attaches to the uterine wall and can happen around the time your period would normally be due.

Implantation bleeding is typically characterized by light pink or brown spotting that lasts only a day or two. It's usually much lighter than a normal period and doesn't require a pad. Many women mistake it for a light period or don't notice it at all.

Other benign causes of early pregnancy bleeding include cervical sensitivity (the cervix becomes more vascular during pregnancy and may bleed slightly after intercourse or a pelvic exam), vaginal irritation, or hormonal fluctuations. These typically don't pose any risk to the pregnancy.

🚨 When to Seek Medical Care for Bleeding

Contact your healthcare provider or seek emergency care if you experience:

  • Heavy bleeding (soaking a pad per hour)
  • Bright red, heavy bleeding
  • Severe abdominal or pelvic pain
  • Dizziness, lightheadedness, or fainting
  • Fever or chills
  • Shoulder tip pain (can indicate ectopic pregnancy)

Find your emergency number →

When Should I Contact a Healthcare Provider?

Contact a prenatal care provider as soon as you have a positive pregnancy test to schedule your first appointment, which typically occurs between weeks 8-12. Seek immediate medical care for severe abdominal pain, heavy bleeding, severe dizziness, or fever. Early prenatal care is important for monitoring your pregnancy and identifying any potential issues early.

Starting prenatal care early is one of the most important things you can do for a healthy pregnancy. Even though your first prenatal visit may not be scheduled until weeks 8-12, contacting a healthcare provider early allows them to give you important guidance about nutrition, prenatal vitamins, medications to avoid, and lifestyle factors.

During your first prenatal visit, your healthcare provider will typically confirm the pregnancy, estimate your due date, review your medical history, perform blood tests and a physical examination, and discuss prenatal care plans. They may also perform an ultrasound to confirm the pregnancy location and viability.

In the meantime, there are several things you can do to support your pregnancy:

  • Take prenatal vitamins: If you haven't already started, begin taking a prenatal vitamin with at least 400 micrograms of folic acid daily
  • Avoid alcohol: There is no known safe amount of alcohol during pregnancy
  • Avoid smoking and drugs: These can harm your developing baby
  • Review medications: Check with your provider about any medications you're taking
  • Eat a balanced diet: Focus on nutrient-rich foods and stay hydrated
  • Limit caffeine: Most guidelines recommend limiting caffeine to 200mg daily (about one 12oz cup of coffee)
Folic Acid is Critical

Folic acid supplementation is especially important during weeks 5-10 when the neural tube is forming. Adequate folic acid intake (at least 400 micrograms daily, 800 micrograms for those with certain risk factors) significantly reduces the risk of neural tube defects such as spina bifida. If you haven't been taking folic acid, start immediately.

What to Expect in the Coming Weeks

The coming weeks represent the most critical period of organ development. During weeks 5-10, all major organ systems form, including the heart (which begins beating around week 6), brain, spinal cord, limbs, and facial features. By week 8, the embryo is called a fetus, and by week 12, most critical development is complete and miscarriage risk decreases significantly.

Understanding what lies ahead can help you prepare for the changes to come. The next several weeks are filled with rapid development and transformation, both for your baby and for your body.

Week 6: The heart begins to beat and may be visible on an ultrasound. Arm and leg buds appear. The embryo is about 4-5mm long.

Week 7: Facial features begin to form including eyes, nostrils, and ears. The brain is growing rapidly. The embryo is about 10mm long.

Week 8: The embryo is now called a fetus. Fingers and toes begin to form, though still webbed. All essential organs have begun to develop. The fetus is about 16mm long.

Weeks 9-12: Bones begin to harden, external genitalia start to differentiate, and the fetus begins to move (though you won't feel it yet). By week 12, the risk of miscarriage decreases significantly, and many couples choose to share their pregnancy news.

Your symptoms may intensify over the coming weeks, particularly morning sickness and fatigue, before typically improving in the second trimester. Hang in there - for most women, energy returns and nausea subsides after weeks 12-14.

Frequently Asked Questions About Pregnancy Week 5

Medical References and Sources

This article is based on current medical research and international guidelines. All claims are supported by scientific evidence from peer-reviewed sources.

  1. American College of Obstetricians and Gynecologists (ACOG). (2024). "Guidelines for Perinatal Care." 9th Edition. ACOG Comprehensive guidelines for prenatal care and early pregnancy management.
  2. World Health Organization (WHO). (2023). "WHO Recommendations on Antenatal Care for a Positive Pregnancy Experience." WHO Publications Global guidelines for antenatal care.
  3. National Institute for Health and Care Excellence (NICE). (2024). "Antenatal Care: NICE Guideline [NG201]." NICE Guidelines Evidence-based recommendations for antenatal care in the UK.
  4. Moore KL, Persaud TVN, Torchia MG. (2023). "The Developing Human: Clinically Oriented Embryology." 11th Edition. Elsevier. Authoritative textbook on human embryology and fetal development.
  5. Cunningham FG, et al. (2022). "Williams Obstetrics." 26th Edition. McGraw-Hill. Comprehensive obstetrics reference text.
  6. Royal College of Obstetricians and Gynaecologists (RCOG). (2024). "Early Pregnancy Guidelines." RCOG Clinical guidelines for early pregnancy care.

Evidence grading: This article uses the GRADE framework for evidence-based medicine. Information about embryonic development is based on established embryological science. Clinical recommendations follow current international guidelines.

iMedic Medical Editorial Team

Specialists in obstetrics, gynecology, and reproductive medicine

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