Newborn Baby Acne: Causes, Symptoms & When to Worry

Medically reviewed | Last reviewed: | Evidence level: 1A
More than half of all newborn babies develop so-called newborn baby acne, medically known as erythema toxicum neonatorum. These harmless spots often appear bumpy and can vary in size. Despite the alarming-sounding medical name, this condition has nothing to do with toxins or infections. The rash is completely harmless, not contagious, and will disappear on its own without any treatment.
📅 Published:
⏱️ Reading time: 8 minutes
Written and reviewed by iMedic Medical Editorial Team | Specialists in Pediatrics

📊 Quick facts about newborn baby acne

How Common
50-70% of babies
Full-term newborns
Appears
1-4 days old
After birth
Duration
Days to 2 months
Self-resolving
Treatment
None needed
Completely benign
Contagious
No
Not infectious
ICD-10 Code
P83.1
Erythema toxicum

💡 The most important things parents need to know

  • Extremely common: More than half of all healthy newborns get these spots - it's a normal part of adjusting to life outside the womb
  • Completely harmless: Despite the medical name containing "toxic," this condition has nothing to do with toxins, allergies, or infections
  • No treatment needed: The rash will disappear on its own within days to a couple of months
  • Not contagious: Your baby cannot spread this to other babies or family members
  • When to worry: Seek medical care if your baby also has fever, seems unwell, or is not feeding properly
  • Comes and goes: The spots may appear more prominent when your baby is warm and can move around the body

What Is Newborn Baby Acne (Erythema Toxicum)?

Newborn baby acne, medically called erythema toxicum neonatorum (ETN), is a common, harmless skin rash that affects 50-70% of full-term newborns. It appears within the first 1-4 days of life as blotchy, bumpy spots and resolves completely without treatment. Despite its name, it has nothing to do with toxins or hormones.

It is very common for newborn babies to develop spots, rashes, or dry, flaky skin. In most cases, this is nothing to worry about and requires no treatment. Newborn baby acne is one of the most common skin conditions in newborns, occurring shortly after birth as a reaction to the new environment the baby encounters outside the sterile conditions of the womb.

The medical term for this condition is erythema toxicum neonatorum, which literally translates to "toxic redness of the newborn." However, this name is misleading and purely historical. The condition has absolutely nothing to do with toxins, poisons, or anything harmful. It is simply an outdated medical term that has persisted despite its inaccurate implications.

The rash is also sometimes called "newborn rash," "toxic erythema," or "baby acne," though it differs from true acne that can occur in older infants. Understanding what causes this condition can help parents feel reassured when they notice these spots on their newborn's skin.

Why Does This Happen to So Many Babies?

Researchers believe erythema toxicum occurs as part of the baby's immune system developing and adjusting to the new world outside the womb. Inside the uterus, the baby exists in a largely sterile, protected environment surrounded by amniotic fluid. Once born, the baby's skin is suddenly exposed to air, temperature changes, bacteria, and countless new substances.

This transition triggers a response in the skin as the immune system begins to recognize and respond to its new environment. The rash represents this normal, healthy adjustment process. Studies have shown that the fluid in the bumps contains eosinophils, a type of white blood cell typically associated with allergic responses, though the condition is not actually an allergy.

Interestingly, erythema toxicum is more common in full-term babies than in premature infants. This may be because full-term babies have more mature immune systems that are more ready to react to their new environment. There is no connection to the mother's health during pregnancy, delivery method, or any actions parents take.

Is There a Connection to Hormones?

Despite sometimes being called "hormone spots," there is no scientific evidence that erythema toxicum is caused by maternal hormones. True neonatal acne, which appears later (usually at 2-4 weeks) and looks more like actual pimples, may have hormonal influences. However, erythema toxicum appears much earlier and has a different cause related to immune system activation.

What Are the Symptoms of Newborn Baby Acne?

Newborn baby acne appears as irregular-shaped, blotchy spots ranging from 2-10 millimeters in size, often with small yellow-white bumps in the center. On lighter skin, the surrounding area appears red; on darker skin, the area may appear darker or only the yellowish bumps may be visible. The spots can come and go, appearing more visible when the baby is warm.

The rash typically appears when the baby is between one and four days old, though it can occasionally appear during the first two weeks of life. The appearance is quite distinctive, which helps healthcare providers distinguish it from other newborn skin conditions that may require treatment.

Each spot has an irregular shape rather than being perfectly round. The spots vary in size, ranging from about 2 millimeters to 10 millimeters in diameter. Many spots have a small yellow or white bump in the center, giving them the appearance of tiny pimples or small blisters. However, these are not infected - despite looking similar to pustules, they contain no bacteria or pus.

When you gently run your hand over the affected skin, it feels bumpy or grainy, which is one of the characteristic signs of this condition. This texture is caused by the raised bumps within the rash areas.

How Does the Rash Appear on Different Skin Tones?

The appearance of erythema toxicum varies depending on your baby's skin color, which is important for parents to understand when identifying this condition:

  • On lighter skin: The spots appear with a characteristic red, blotchy background surrounding the central yellowish bumps. The redness can be quite pronounced, sometimes alarming parents who worry their baby has an infection or allergic reaction.
  • On darker skin: The redness may be less visible or appear as a darker discoloration of the skin. Sometimes only the yellow-white central bumps are visible, with the surrounding skin showing subtle changes in pigmentation rather than obvious redness.

The skin may look blotchy or mottled, and the red coloring (or darker pigmentation) can come and go throughout the day. Many parents notice that the spots become more visible when the baby is warm, such as after feeding, when held close, or after being bundled in blankets. The spots may seem to fade when the baby cools down, only to reappear when warm again.

Where on the Body Do the Spots Appear?

The rash most commonly appears on specific areas of the body, though it can occur almost anywhere:

  • Face: Very common location, particularly on the cheeks, forehead, and chin
  • Neck: Frequently affected, especially in skin folds
  • Chest: A common location for the rash
  • Abdomen: Often shows spots
  • Arms and thighs: Sometimes affected, though less commonly than the trunk

The palms of the hands and soles of the feet are typically spared, which can help differentiate this condition from other newborn rashes. The rash can also seem to "migrate" or move around the body - spots may fade in one area while new ones appear elsewhere. This moving pattern is completely normal and not a sign that the condition is worsening.

How Long Does the Rash Last?

The duration of erythema toxicum varies from baby to baby, but parents can generally expect the following timeline:

  • Shortest duration: Some babies have spots that last only a few days
  • Average duration: Most cases resolve within one to two weeks
  • Longest duration: In some cases, the rash can persist for up to two months, though this is less common

Throughout this time, no treatment is needed or recommended. The condition is not itchy or painful for your baby, so there is no discomfort that needs to be addressed. Your baby will behave normally, feeding and sleeping as usual, completely unaffected by the appearance of the rash.

When Should You See a Doctor for Your Newborn's Rash?

Seek immediate medical attention if your newborn has a rash combined with fever, unusual drowsiness, poor feeding, or signs of illness. These could indicate an infection requiring urgent treatment. Most newborn baby acne (erythema toxicum) does not require medical care as it resolves on its own.

Erythema toxicum typically resolves completely on its own, and most parents do not need to seek medical care. However, it is natural to feel uncertain about whether your baby's rash is truly harmless, especially as a new parent. Healthcare providers are accustomed to these questions and are happy to provide reassurance.

If you feel unsure or worried about your newborn's skin, you can contact your pediatrician, family doctor, or well-baby clinic. During the first week of life, you can also reach out to the birthing center or hospital where you delivered for guidance. Most of the time, healthcare providers can reassure you over the phone or during a routine visit.

Warning Signs That Require Immediate Medical Attention

🚨 Seek emergency care immediately if your baby has a rash AND:
  • Fever - Any temperature of 38°C (100.4°F) or higher in a newborn requires immediate evaluation
  • Unusual drowsiness or lethargy - Baby is harder to wake or less alert than usual
  • Poor feeding - Refusing to eat or eating much less than normal
  • Irritability - Excessive crying or difficulty consoling
  • Signs of infection - Spreading redness, warmth, swelling, or pus
  • Blisters with fluid - Especially if they appear in clusters

These symptoms could indicate a serious infection such as neonatal herpes or bacterial sepsis, which require urgent medical treatment. Find your emergency number →

The key distinction is that babies with erythema toxicum are otherwise completely well. They feed normally, sleep normally, have no fever, and show no signs of distress. If your baby has a rash but seems perfectly healthy and happy otherwise, the rash is very likely to be harmless erythema toxicum.

Conditions That Can Look Similar

Several other skin conditions can occur in newborns, and while most are also harmless, some require medical attention. Understanding these differences can help parents know when to seek care:

Newborn skin conditions: differences and when to seek care
Condition Appearance When it appears Action needed
Erythema toxicum (baby acne) Red blotchy spots with yellow-white bumps 1-4 days after birth No treatment needed
Milia Tiny white bumps, especially on nose and cheeks Present at birth No treatment needed
Neonatal acne Red pimples similar to teenage acne 2-4 weeks old Usually resolves alone; see doctor if severe
Neonatal herpes Clusters of blisters, often with fever First 2 weeks Emergency - seek care immediately

Does Newborn Baby Acne Need Treatment?

No treatment is needed for newborn baby acne (erythema toxicum). The condition is completely benign and will resolve on its own within days to weeks. Do not apply creams, lotions, or attempt to pop or squeeze the bumps. Simply keep your baby's skin clean with normal gentle bathing.

One of the most reassuring aspects of erythema toxicum is that it requires absolutely no treatment. Unlike many other skin conditions, there is nothing parents need to do to help the rash go away faster. In fact, trying to treat it may potentially irritate the skin unnecessarily.

The rash is not painful or itchy for your baby. Your little one is not experiencing any discomfort from these spots, even if they look concerning to you. Babies with erythema toxicum behave exactly the same as babies without it - they eat, sleep, and go about their newborn business without any awareness of their rash.

What Should You Avoid Doing?

While the temptation to "do something" about the rash is understandable, it's important to avoid certain actions that could potentially cause harm:

  • Do not pop or squeeze the bumps: Unlike actual pimples, these bumps are not filled with material that needs to be expressed. Squeezing them could damage the delicate newborn skin and potentially introduce bacteria, leading to actual infection.
  • Do not apply creams or lotions: Baby lotions, acne treatments, hydrocortisone cream, or any other products are not needed and may irritate the skin.
  • Do not scrub the affected areas: Aggressive cleaning will not help the rash resolve faster and may cause irritation.
  • Do not use harsh soaps: Stick to gentle, fragrance-free baby cleansers or plain water for bathing.

General Newborn Skin Care Tips

While no specific treatment is needed for erythema toxicum, following good general newborn skin care practices will help keep your baby's skin healthy:

Basic newborn skin care:
  • Bathe your baby every few days with lukewarm water and gentle, fragrance-free cleanser
  • Pat skin dry gently rather than rubbing
  • Keep skin folds clean and dry
  • Dress baby in soft, breathable fabrics
  • Avoid overdressing or overheating
  • Use fragrance-free laundry detergent for baby clothes and bedding

What Causes Newborn Baby Acne?

Erythema toxicum is caused by the newborn's immune system responding to the new environment outside the womb. It is not caused by hormones, allergies, infections, or anything the parents did. The rash represents a normal, healthy adaptation process that occurs in most full-term babies.

The exact mechanism that triggers erythema toxicum is still being studied by researchers, but the current understanding points to the immune system's role in adaptation to extrauterine life. When a baby is born, their skin suddenly encounters a completely new world full of air, temperature variations, bacteria, and countless other substances.

Inside the womb, the baby floated in amniotic fluid in a relatively sterile environment. The skin was never exposed to air, clothing, or the normal bacteria that colonize human skin. Once born, the baby's immune system must quickly learn to recognize and tolerate these new exposures while still being ready to fight actual threats.

Researchers have found that the bumps in erythema toxicum contain eosinophils, a type of white blood cell. Eosinophils are typically associated with allergic reactions and parasitic infections. However, in the case of erythema toxicum, their presence appears to represent an innate immune response rather than a true allergy. The skin is essentially "practicing" its immune response as it adapts to the outside world.

Risk Factors and Who Gets It

Erythema toxicum occurs in approximately 50-70% of full-term newborns, making it more common to have it than not to have it. Some factors that may influence whether a baby develops this rash include:

  • Gestational age: Full-term babies are more likely to develop erythema toxicum than premature infants. This may be because full-term babies have more mature immune systems.
  • Birth weight: Babies with higher birth weights may be slightly more likely to develop the rash.
  • Mode of delivery: Some studies suggest a slightly higher incidence in babies born vaginally compared to cesarean delivery, but this is not consistently found.

Importantly, there is no connection between erythema toxicum and maternal health, diet during pregnancy, medications, stress levels, or any actions the parents took. It is simply a normal occurrence that happens to most babies.

What Is the Long-Term Outlook?

The prognosis for erythema toxicum is excellent - it always resolves completely with no lasting effects. The rash does not leave scars, does not recur, and is not associated with any long-term skin problems or health issues. Once it clears, the skin returns to completely normal.

Parents can be completely reassured about the long-term outlook for their baby. Erythema toxicum is a temporary condition that leaves absolutely no lasting effects on the skin or the baby's health. Once the rash has cleared, it does not come back, and the skin that was affected looks completely normal.

Unlike some skin conditions that can leave pigmentation changes or scarring, erythema toxicum heals without a trace. There is no need for follow-up visits specifically for this condition, and no special monitoring is required.

Additionally, having erythema toxicum does not mean your baby is more likely to develop skin problems, allergies, or any other conditions later in life. It is simply a one-time, normal response to being born that has no implications for future health.

Frequently Asked Questions About Newborn Baby Acne

Medical References and Sources

This article is based on current medical research and international guidelines. All claims are supported by scientific evidence from peer-reviewed sources.

  1. Cutis. Erythema Toxicum Neonatorum: A Review (2023). Comprehensive dermatology review of erythema toxicum neonatorum. Evidence level: 1A
  2. American Academy of Pediatrics (AAP). (2024). "Newborn Skin Care Guidelines." Official AAP recommendations for newborn skin care and common skin conditions.
  3. World Health Organization (WHO). (2023). "WHO Recommendations on Newborn Health." WHO Publications International guidance on essential newborn care.
  4. Pediatric Dermatology, 6th Edition (2022). Editors: Schachner LA, Hansen RC. Standard reference textbook on pediatric skin conditions.
  5. Journal of the American Academy of Dermatology (2021). "Neonatal Dermatology: An Updated Review." Peer-reviewed update on neonatal skin conditions including erythema toxicum.
  6. Archives of Disease in Childhood - Fetal and Neonatal Edition (2020). "Common benign skin rashes in neonates." Clinical review differentiating benign from concerning neonatal rashes.

Evidence grading: This article uses the GRADE framework (Grading of Recommendations Assessment, Development and Evaluation) for evidence-based medicine. Evidence level 1A represents the highest quality of evidence, based on systematic reviews of randomized controlled trials and cohort studies.

⚕️

iMedic Medical Editorial Team

Specialists in Pediatrics and Neonatology

Our Editorial Team

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